Scaling Agentic Inference Across Heterogeneous Compute with Zain Asgar - #757
In this episode, Zain Asgar, co-founder and CEO of Gimlet Labs, joins us to discuss the heterogeneous AI inference across diverse hardware. Zain argues that the current industry standard of running all AI workloads on high-end GPUs is unsustainable for agents, which consume significantly more tokens than traditional LLM applications. We explore Gimlet’s approach to heterogeneous inference, which involves disaggregating workloads across a mix of hardware—from H100s to older GPUs and CPUs—to optimize unit economics without sacrificing performance. We dive into their "three-layer cake" architecture: workload disaggregation, a compilation layer that maps models to specific hardware targets, and a novel system that uses LLMs to autonomously rewrite and optimize compute kernels. Finally, we discuss the complexities of networking in heterogeneous environments, the trade-offs between numerical precision and application accuracy, and the future of hardware-aware scheduling.
The complete show notes for this episode can be found at https://twimlai.com/go/757.
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Proactive Agents for the Web with Devi Parikh - #756
Today, we're joined by Devi Parikh, co-founder and co-CEO of Yutori, to discuss browser use models and a future where we interact with the web through proactive, autonomous agents. We explore the technical challenges of creating reliable web agents, the advantages of visually-grounded models that operate on screenshots rather than the browser’s more brittle document object model, or DOM, and why this counterintuitive choice has proven far more robust and generalizable for handling complex web interfaces. Devi also shares insights into Yutori’s training pipeline, which has evolved from supervised fine-tuning to include rejection sampling and reinforcement learning. Finally, we discuss how Yutori’s “Scouts” agents orchestrate multiple tools and sub-agents to handle complex queries, the importance of background, "ambient" operation for these systems, and what the path looks like from simple monitoring to full task automation on the web.
The complete show notes for this episode can be found at https://twimlai.com/go/756.
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AI Orchestration for Smart Cities and the Enterprise with Robin Braun and Luke Norris - #755
Today, we're joined by Robin Braun, VP of AI business development for hybrid cloud at HPE, and Luke Norris, co-founder and CEO of Kamiwaza, to discuss how AI systems can be used to automate complex workflows and unlock value from legacy enterprise data. Robin and Luke detail high-impact use cases from HPE and Kamiwaza’s collaboration on an “Agentic Smart City” project for Vail, Colorado, including remediation and automation of website accessibility for 508 compliance, digitization and understanding of deed restrictions, and combining contextual information with camera feeds for fire detection and risk assessment. Additionally, we discuss the role of private cloud infrastructure in overcoming challenges like cost, data privacy, and compliance. Robin and Luke also share their lessons learned, including the importance of fresh data, and the value of a "mud puddle by mud puddle" approach in achieving practical AI wins.
The complete show notes for this episode can be found at https://twimlai.com/go/755.
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Building an AI Mathematician with Carina Hong - #754
In this episode, Carina Hong, founder and CEO of Axiom, joins us to discuss her work building an "AI Mathematician." Carina explains why this is a pivotal moment for AI in mathematics, citing a convergence of three key areas: the advanced reasoning capabilities of modern LLMs, the rise of formal proof languages like Lean, and breakthroughs in code generation. We explore the core technical challenges, including the massive data gap between general-purpose code and formal math code, and the difficult problem of "autoformalization," or translating natural language proofs into a machine-verifiable format. Carina also shares Axiom's vision for a self-improving system that uses a self-play loop of conjecturing and proving to discover new mathematical knowledge. Finally, we discuss the broader applications of this technology in areas like formal verification for high-stakes software and hardware.
The complete show notes for this episode can be found at https://twimlai.com/go/754.
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High-Efficiency Diffusion Models for On-Device Image Generation and Editing with Hung Bui - #753
In this episode, Hung Bui, Technology Vice President at Qualcomm, joins us to explore the latest high-efficiency techniques for running generative AI, particularly diffusion models, on-device. We dive deep into the technical challenges of deploying these models, which are powerful but computationally expensive due to their iterative sampling process. Hung details his team's work on SwiftBrush and SwiftEdit, which enable high-quality text-to-image generation and editing in a single inference step. He explains their novel distillation framework, where a multi-step teacher model guides the training of an efficient, single-step student model. We explore the architecture and training, including the use of a secondary 'coach' network that aligns the student's denoising function with the teacher's, allowing the model to bypass the iterative process entirely. Finally, we discuss how these efficiency breakthroughs pave the way for personalized on-device agents and the challenges of running reasoning models with techniques like inference-time scaling under a fixed compute budget.
The complete show notes for this episode can be found at https://twimlai.com/go/753.
About The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)
Machine learning and artificial intelligence are dramatically changing the way businesses operate and people live. The TWIML AI Podcast brings the top minds and ideas from the world of ML and AI to a broad and influential community of ML/AI researchers, data scientists, engineers and tech-savvy business and IT leaders. Hosted by Sam Charrington, a sought after industry analyst, speaker, commentator and thought leader. Technologies covered include machine learning, artificial intelligence, deep learning, natural language processing, neural networks, analytics, computer science, data science and more.
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