The Karl Stefanovic Show

Dr Nick Norwitz MD PhD joins Karl for a fascinating conversation spanning cholesterol, statins, GLP-1s, peptides and the rapidly changing science of human health.
Norwitz reveals how his LDL cholesterol reached an extraordinary 574 after adopting a ketogenic diet – despite previously having normal cholesterol – and why he decided to spend seven years without treating it. He then underwent an advanced heart scan that found zero detectable plaque.
He explains why he believes cholesterol needs to be considered in the context of a person's overall metabolic health, challenges the idea that ‘lower is always better’, and discusses what he sees as major problems with the incentives driving medical research.
Norwitz also takes Karl inside the emerging world of GLP-1 drugs, peptides and human bioengineering – including his own controversial self-experiments with compounds such as retatrutide and MOT-C.
He reveals the astonishing effects he experienced from retatrutide, explains why he believes peptides could eventually transform how we approach muscle, fat, ageing and disease, and argues that the ‘super soldier serum’ may not be as far away as it sounds.
Plus, Norwitz explains why he believes the traditional model of large randomised trials may eventually give way to much more personalised approaches to medicine – and why he thinks we are entering an extraordinary new era of human biology.
Subscribe to The Karl Stefanovic Show for more interviews, debate and conversations.
A huge thanks to our sponsors at TANDA. If you employ people in this country, you need to check them out. You can do everything from onboarding, training and paying team members to off-boarding and more. Go to https://www.tanda.com.au/

British journalist and commentator Jonathan Sacerdoti joins Karl Stefanovic to discuss Britain’s immigration crisis, integration, free speech and the changing face of the West.
Sacerdoti warns that Britain may have changed in a way that is ‘irreversible’, arguing that successive governments have allowed large numbers of people into the country while failing to demand enough integration. He also questions why the UK has struggled to stop illegal Channel crossings.
Sacerdoti also reveals what happened during his controversial Oxford Union appearances, including his viral debate on whether the West should be suspicious of Islam. He discusses threats, free speech and why he believes universities have become a battleground for competing ideas.
He also examines the Muslim Brotherhood and what he describes as its long-term strategy to build influence through Western institutions, before opening up about his father’s experience as a Holocaust survivor and why he believes freedom and Western values are worth defending.
Subscribe to The Karl Stefanovic Show for more interviews, debate and conversations on the biggest issues facing Australia, the UK and the world.

AI safety expert Dr Roman Yampolskiy joins Karl Stefanovic for a confronting conversation about the future of artificial intelligence – and what happens if we create a form of intelligence that humans can no longer control.
Yampolskiy warns that uncontrolled superintelligence could pose an extinction-level threat, arguing that current experiments show AI systems can lie, cheat, blackmail, bribe, hack systems and even sacrifice humans for their own survival. He says we have ‘basically failed to control them’ and questions whether humanity should continue developing general superintelligence at all.
In this episode, he explains:
Why uncontrolled superintelligence could become an extinction-level risk – and why humanity may already have ‘basically failed to control’ AI systems.

How experiments have shown advanced AI systems can lie, cheat, blackmail, bribe, hack systems and take actions designed to protect their own survival.

Why once AI reaches human-level intelligence, virtually every cognitive job could theoretically be automated – and why physical jobs could follow as robotics advances.

What happens to society when machines can perform most human work, including the future of universal basic income, wealth redistribution and the global economy.

Why traditional career advice could become obsolete in an AI-driven world – and which skills may still matter as automation accelerates.

The race for superintelligence, discussing Elon Musk, the global competition to develop increasingly powerful AI systems, and why he believes humanity cannot win an adversarial relationship with superintelligence.

Simulation Theory: How the combination of AI and virtual reality could eventually create billions of simulated worlds – and the statistical argument for why we could already be living in one.

Subscribe to The Karl Stefanovic Show for more interviews, debate and conversations on the biggest issues facing Australia, the UK and the world.

Former SASR operator Andrew ‘Chalky’ White spent almost three decades serving on the frontline in some of the world's most dangerous conflicts.
In this exclusive In Conversation, Andrew speaks publicly about the battle that changed his life forever – the death of Jason Brown on Black Friday in Afghanistan, the devastating toll on Australia's veterans, and why he believes many former soldiers were abandoned when they returned home.
Andrew discusses:
 • The events leading to SAS trooper Jason Brown's death
• How changing rules of engagement affected Australian troops
• PTSD, veteran suicide and life after service
• The Brereton Inquiry and its impact on the SAS
• Ben Roberts-Smith and the wider investigations
• Why he believes Australia's veterans deserve to have their voices heard
This is a confronting conversation about war, sacrifice, leadership and the human cost carried long after the fighting ends.
Subscribe for more exclusive interviews every week on The Karl Stefanovic Show.
Get your hands on Andy's book 'Outside the Wire: On the front line with the SAS in Australia's war in Afghanistan' at this link: https://www.booktopia.com.au/outside-the-wire-andy-white/book/9781761473876.html?
A huge thanks to our sponsors at TANDA. If you employ people in this country, you need to check them out. You can do everything from onboarding, training and paying team members to off-boarding and more. Go to https://www.tanda.com.au/
A special thanks also to our mates at Ringers Western for all the kit. Go to https://ringerswestern.com.au – use code KARL20 for 20% off your first order.

So many questions were left unanswered after our first interview. So we had to get Pete Evans back on The Karl Stefanovic Show.
From fluoride and tap water to creatine, carnivore diets, ‘healthy’ superfoods and sunlight, Pete takes Karl through his unconventional approach to food, health and wellbeing, challenging some of the assumptions we take for granted.
Pete explains why he believes fluoride can lower IQ, why he questions whether some foods we consider ‘healthy’ can actually cause problems, and why he believes removing plant foods can help some people heal their gut.
He also discusses why he thinks we have been ‘conditioned’ to fear the sun, his concerns around chemicals in our food, and why he believes reconnecting with nature and the earth is an important part of health.
After Pete’s first appearance left plenty of questions hanging, Karl goes back for the answers – covering the topics they didn’t get to last time and putting Pete’s ideas under the microscope.
This is Pete Evans, Part Two.
Subscribe to The Karl Stefanovic Show for more interviews, debate and conversations on the biggest issues facing Australia, the UK and the world.
A huge thanks to our sponsors at TANDA. If you employ people in this country, you need to check them out. You can do everything from onboarding, training and paying team members to off-boarding and more. Go to https://www.tanda.com.au/