This week’s guest is Leslie Berlin, the author, historian and executive director of the Steve Jobs Archive.My first encounter with Berlin’s work happened when I picked up The Man Behind the Microchip: Robert Noyce and the Invention of Silicon Valley, which is Berlin’s biography of the Fairchild Semiconductor and Intel co-founder. Noyce, of course, was many things. He co-invented the integrated circuit and reshaped the trajectory of the world in the process. He ran one of Silicon Valley’s most iconic companies. He mentored people like Steve Jobs. And he was the Valley’s first real engineer playboy star.Berlin’s book is one of my all-time favorite reads and a wonderful example of what a biography can be. Berlin, of course, is many things as well. She’s been one of the most influential historians when it comes to Silicon Valley and the technology industry. She used to run Silicon Valley Archives at Stanford University, and now heads up the Steve Jobs Archive. Berlin is also the author of another tremendous book - Troublemakers: Silicon Valley's Coming of Age, which chronicles the work of several people who had distinctive roles across the tech industry.In this chat, we get into Noyce’s life and what he meant to Silicon Valley, the semiconductor industry, the fall of Intel, the Valley’s history overall and Berlin’s current work.There’s basically no one I would rather talk to, and we’re thrilled that Berlin joined the pod.Huge thanks to everyone who has been supporting the Core Memory podcast. It’s been surging up the charts of late. We’re grateful. Don’t be shy. Tell your friends.A huge thanks, as always, as well to E1 Ventures for they are noble venture capitalists who have great taste and have backed us from the start. Follow them on X. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe
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1:23:54
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1:23:54
The Iranian Scientist Leading America’s Nuclear Rebirth
Our guests this week are Kurt Terrani, an Iranian-born nuclear scientist, and Tommy Hendrix, a Green Beret turned venture capitalist, and they arrive with an exceptional story.Terrani is the co-founder and CEO of Standard Nuclear, and Hendrix is the company’s Chairman and main investor through his firm Decisive Point. Standard has started making a nuclear reactor fuel known as TRISO (Tri-structural ISOtropic) that comes with the promise of being very safe and with the ability to power a new breed of small nuclear reactors that can be placed anywhere someone needs a lot of power.Standard Nuclear popped out of stealth mode last month via a fascinating story in The Wall Street Journal.It turns out that Standard’s predecessor - Ultra Safe Nuclear – had been backed for years by a wealthy ex-CIA operative named Richard Hollis Helms. When Helms passed away in 2024, the company was left in financial peril. Terrani and Hendrix pulled the venture out of bankruptcy and saved its prized TRISO technology.As we explain in the episode, TRISO is a type of nuclear reactor fuel that the U.S. has been working on for decades. It places a protective coating around fuel particles that makes them incredibly safe, and the U.S. and other countries have proven this out through vast amounts of research. China, of course, has TRISO reactors already as does Germany.Standard Nuclear hopes to make a lot of TRISO for a coming wave of nuclear start-ups building SMRs, or Small Modular Reactors. These reactors come in various shapes and sizes, but the general idea is that they’re small enough to be shipped to any place that needs serious power – be it an AI data center, an overseas Army supply line or even an industrial hub in space.I recently visited Standard’s TRISO plant in Tennessee, which is right next door to Oak Ridge National Laboratory where Terrani and much of his team used to work. We’ll have a video on the visit coming soon.During our chat, we get into the U.S.’s nuclear failings and aspirations, Standard’s wild history and the future of nuclear technology.This episode was made possible by the fine people at E1 Ventures. You can find them here and on X here. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe
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1:15:43
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1:15:43
Priscilla Chan and Her Multi-Billion Dollar Quest to End Disease
Ten years ago, Dr. Priscilla Chan and Mark Zuckerberg vowed to aim almost all of their billions at a singular goal: “to cure, prevent and manage all disease by the end of this century.”Dr. Chan recently visited the Core Memory podcast studio to discuss CZI, aka the Chan Zuckerberg Initiative, the organization that she and her husband built to pursue this massive undertaking. To date, the couple has put $7 billion toward a broad range of scientific programs and has backed bio-tech centers across the U.S. They’re funding some of the most cutting-edge work on trying to understand how the human body functions at the cellular level and placing some of the riskiest, boldest bets in bio-tech.CZI has not operated without controversy. Over the past few weeks, Dr. Chan has faced criticism for dialing back funding on some of the organization’s education and political programs in favor of going Full Science.We get into this a bit on the show, although, I will Full Confess to being less into telling people how to spend their money than others appear to be.Mostly, we discuss Dr. Chan’s dramatic life story and the work CZI is doing to push bio-tech forward. Recently, for example, the organization backed a new program aimed at trying to cure children struck with genetic rare diseases. CZI has also just put out a new AI-based model that gives us a better understanding of how cells work.Since we’ve recently become a sci-tech and tennis publication, we get into Dr. Chan’s tennis career as well. Enjoy!This podcast was made possible by the fine people at E1 Ventures, who also support science and human progress through their investments. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe
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1:02:14
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1:02:14
Spaceplanes Are Upon Us
Last November, Dawn Aerospace broke some aerospace records. Its spaceplane – the Mk-II Aurora – hit Mach 1.1 on its way to climbing to 20km faster than any aircraft that has ever taken off from a runway. (The previous record was set by an F-15 in 1975.)Dawn, based in New Zealand, now looks to make flying to the edge of space a regular occurrence. Its craft blends rocket engines with a plane design and can carry small payloads (up to 5kg) for defense, science and commercial customers. In June, the company signed a deal with a group in Oklahoma to perform dozens of flights from the Oklahoma Air and Space Port - and, yes, that’s a real thing.We sat down with Stefan Powell, the co-founder, CEO and CTO of Dawn, to talk about spaceplanes, Dawn’s satellite propulsion business and the aerospace scene in New Zealand and Europe.Dawn has moved quite quickly for an aerospace company and, like Rocket Lab before it, stunned the world by doing much of innovation from New Zealand, which has not historically been an aerospace power. Its ability to get to the edge of space and back multiple times a day is unique, and it has plans for even bigger craft in the future.This episode was made possible by the fine people at E1 Ventures, who happen to invest in hard-tech things like aerospace. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe
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1:15:05
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1:15:05
The Child Prodigy Teaching Other People How To Learn
Andrew Hsu has been something of a legend for most of his life.In 2007, The Seattle Times published a story documenting Hsu’s graduation from the University of Washington. He was only 16 and had just picked up three degrees in neurobiology, biochemistry and chemistry.But stories of Hsu’s academic feats had already been circulating for years. He’d won science contests, written an award-winning autobiography and started a foundation to help children in need as an adolescent. Hsu’s family hails from Taiwan, and the young man often found himself being interviewed on TV and touring the country to tell his story.After graduating from college, Hsu pursued a PhD at Stanford before dropping out and using some Thiel Fellowship money to start an ed-tech company called Airy Labs.That company struggled, but Hsu’s latest venture – Speak – has been booming. It’s an AI-powered language tutor that enjoyed immense success first in South Korea and then beyond. It’s been valued at more than $1 billion after a $78 million funding round closed near the end of last year.In this episode, Hsu graciously tolerates my child prodigy questions and then gets into how he hit on AI and language before it was cool and how people can learn better. This episode was made possible by E1 Ventures, backers of bold people and bold ideas. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe
Core Memory is a podcast about science and technology hosted by best-selling author and filmmaker Ashlee Vance.
Vance has spent the past two decades chronicling advances in science and tech for publications like The Economist, The New York Times and Bloomberg Businessweek. Along with the stories, he's written best-selling books like Elon Musk’s biography, made an Emmy-nominated tech TV show watched by millions and produced films for HBO and Netflix. The goal has always been to bring the tales of complex technology and compelling people to the public and give them a path into exceptional and unusual worlds they would not normally have a chance to experience. www.corememory.com