172 episodes
167: When a Stroke Doesn't Look Like a Stroke: Recognizing Basilar Artery Occlusions
24/10/2026 | 47 mins.How do you recognize a stroke when the usual symptoms are present? No facial droop. No slurred speech. No one-sided weakness.
In this episode, you'll hear the case of a post-op patient with normal vital signs but complaints of double vision. What follows is one of the most devastating types of ischemic stroke: a basilar artery occlusion.
Sarah walks through each decision that led to the patient's full recovery, from the bedside nurse's decision to activate the rapid response team, the the RRT nurse calling a stroke alert, to thrombectomy when thrombolytics weren’t an option. She also breaks down when common symptoms like dizziness should raise concern for basilar artery occlusion, why strokes like this one are so easy to miss with your typical FAST exam alone, and how a tour of the brain helps you predict neurological deficits.
Topics discussed in this episode:
Why the nurse called rapid response for a post-op patient
Anterior vs. posterior circulation
Classic vs. atypical presentations of basilar artery occlusion
Why FAST alone can miss posterior circulation strokes
Locked-in syndrome and assessing consciousness
Stroke localization: a tour of the brain
IV thrombolytics: alteplase, tenecteplase, and bleeding risk
When to use mechanical thrombectomy
CT perfusion: core infarct vs. ischemic penumbra
5 important takeaways for your next neuro emergency
The American Heart Association/American Stroke Association's 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke:
https://www.ahajournals.org/doi/10.1161/STR.0000000000000513
Mentioned in this episode:
AND
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This episode was produced by Podcast Boutique https://www.podcastboutique.com- "I feel like I'm drowning." Four days after a STEMI, a patient who had been recovering well is sitting bolt upright, coughing up pink, frothy sputum, and unable to catch his breath.
In this episode, Sarah walks you through a worst-case scenario complication every cardiac nurse needs on their radar: post-MI papillary muscle rupture causing acute, severe mitral regurgitation. This is one of those zebra diagnoses that you may never see... but if you do, recognizing it early is what gets your patient to the OR alive.
Sarah breaks down the pathophysiology behind the patient's sudden deterioration, the clues that will help you catch a mechanical complication, and how to treat the patient — including which medications help (or backfire), and where BiPAP and mechanical support fit in.
Topics discussed in this episode:
Case presentation: sudden respiratory distress 4 days post-STEMI
Mitral valve anatomy and the role of the papillary muscles
Why mechanical complications happen days after an MI
Acute vs. chronic mitral regurgitation
Why the lungs flood while the organs starve
Why murmurs can be misleading
BiPAP and the risks of intubating a patient in shock
Afterload reduction vs. norepinephrine
When Lasix helps and when it doesn't
Mechanical circulatory support: IABP, Impella, and VA-ECMO
How to communicate with a frightened patient 165: Breaking the Storm Part 2: Antiarrhythmics, Sympathetic Blockade, and the Emerging Role of Esmolol
15/07/2026 | 27 mins.The shock worked. The rhythm converted. And then V-fib came right back. Now what?
Part two of this series explores the physiology and pharmacology driving recurrent V-fib so you can respond confidently when shocks aren’t enough.
You'll learn how the body's sympathetic nervous system response keeps the heart unstable, why epinephrine can both help and hurt, when to reach for lidocaine over amiodarone, and what the research says about the emerging role of esmolol to target the storm itself (not just the arrhythmia).
Topics discussed in this episode:
The sympathetic nervous system and cardiac arrest
Why epinephrine both helps and hurts
Amiodarone vs. lidocaine: which is better?
Key findings from the ROC-ALPS trial
Why antiarrhythmics don't replace defibrillation
The evidence behind esmolol in refractory V-fib
3 lessons for codes when ACLS isn't enoughBONUS EPISODE: Rapid Response Calls That Never Should Have Happened from the Nurse Gwenny Podcast
12/07/2026 | 43 mins.This special episode was recorded and released on the Nurse Gwenny Podcast. We talked about some of those early signs of deterioration that are often missed and how we can speak up and advocate before the patient crashes.
Check out this episode and so many more over at the Nurse Gwenny Podcast
And, you can join the Nurse Gwenny Library to earn CE credits for listening to the show!
Use code: rapidresponsern
to get a discount on your membership:
https://library.nursegwenny.com/bundles/nurse-gwenny-library-membership164: Electrical Storm Part 1:The Pathophysiology of Ventricular Storm and the Science of Defibrillation
19/06/2026 | 26 mins.Sometimes V-fib doesn't respond to the shock at all. Sometimes it converts and comes right back. Those are two completely different problems.
In this episode, Sarah breaks down the science behind why defibrillation fails, how to recognize the difference between refractory and recurrent V-fib, and respond when shocks aren't working. You'll learn how to start approaching the electrical storm at the bedside — that means understanding transthoracic impedance, optimizing your pad placement, and knowing when to reach for double sequential defibrillation.
Topics discussed in this episode:
Refractory vs. recurrent V-fib
The physiology of ventricular fibrillation and re-entry tachycardias
Misconceptions about defibrillation
Transthoracic impedance and how to reduce it
Anterior-lateral vs. anterior-posterior pad placement
Double sequential defibrillation: evidence and objections
Key findings from the DOSE VF trial
American Heart Association. (2025). 2025 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation.
Cheskes, S., Dorian, P., Feldman, M., McLeod, S., Scales, D. C., Pinto, R., Turner, L., Morrison, L. J., Drennan, I. R., & Verbeek, P. R. (2020). Double sequential external defibrillation for refractory ventricular fibrillation: The DOSE VF pilot randomized controlled trial. Resuscitation, 150, 178–184. https://doi.org/10.1016/j.resuscitation.2020.02.010
D. Hasegawa, A. Sharma, Y. I. Lee, & R. Sato. (2023). A systematic review and meta-analysis of esmolol for refractory ventricular fibrillation and pulseless ventricular tachycardia. Chest, 164(4 Suppl.), A1568. https://doi.org/10.1016/j.chest.2023.07.1077
International Liaison Committee on Resuscitation. (2025). 2025 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations (CoSTR).
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About Rapid Response RN
Do you want to go from dreading emergencies to feeling confident and ready to jump into action to rescue your patient?
Well, this show will let you see emergencies unfold through the eyes of a Rapid Response Nurse. With real life stories from the frontlines of nursing, host Sarah Lorenzini MSN, RN, CCRN, CEN, a Rapid Response Nurse and educator, shares her experiences at rapid response events and breaks down the pathophysiology, pharmacology, and the important role the nurse plays during emergencies.
If you want to sharpen your assessment skills and learn how to think like a Rapid Response Nurse, then Sarah is here to share stories, tips, tricks, and mindsets that will prepare you to approach any emergency.
Every episode is packed full of exactly what you need to know to handle whatever crisis that could arise on your shift. It’s one thing to get the right answer on the test, but knowing how to detect when YOUR patient is declining and what to do when YOUR patient is crashing is what will make or break your day… and might just save your patient’s life.
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