278 episodes
- Creatine has long been associated with bodybuilding and strength training — but its potential benefits extend far beyond the gym. In this episode, Kris Gethin dives into the evolving research on creatine's impact on cognitive function, mental health, and even its role during periods of sleep deprivation.
Chapters
00:00 Introduction to creatine's expanding benefits
02:16 Research on creatine and cognitive performance
04:31 Creatine's relevance for sleep-deprived individuals
06:44 Creatine's potential in anxiety and mental health
09:25 The challenge of increasing brain creatine levels
09:52 GAA as a precursor to enhance creatine levels
11:17 Research on GAA and cognitive performance
12:15 Future directions: brain-focused creatine research
13:09 Personal insights and practical applications of creatine
14:35 Conclusion and next steps for research and health
Resources & Links
💪 Shop Unmatched Supps Creatine
This content is for informational purposes only and is not medical advice. Talk to your doctor before starting any new supplement, especially if you are pregnant, managing a health condition, or taking prescribed medication for depression or other mood disorders. 275. How Your Water Could Be Affecting Your Pump, Recovery & Physique with Alex Kikel
10/09/2026 | 1h 21 mins.Most bodybuilders have been taught to think about water in one way: drink enough of it and stay hydrated. So it makes sense that the real attention goes to the things we have been told actually move the needle: protein, carbs, creatine, electrolytes, pre-workout, recovery, blood work, and everything else in the stack. But once you start looking at what water is doing inside muscle tissue, what can be in the water you are drinking, and how much of it you put through your body every day, it becomes difficult to treat it as just the liquid you wash your supplements down with.
In this episode, Alex Kikel joins me to bring a completely different perspective to something most of us have never had a reason to question. We get into why the type of water you drink could matter for muscle contractions, pumps, glycogen storage, recovery, and cognition, along with what could be coming from tap and bottled water. We also get into structured water, filtration, remineralization, hydrogen water, and then take it straight into contest prep with fluid retention, sodium, creatine, and why cutting water can sometimes leave a bodybuilder looking flatter instead of tighter.
Alex has spent 14 years working with and tracking thousands of people, including Olympic, NBA, and NFL athletes. His experience across health, physique, and high-level performance gives us a very different way to look at something bodybuilders use every day but rarely treat as part of the protocol itself.
What's Discussed:
04:55 Why the water inside your muscles could affect contractions, pumps, strength, and how much you get from every rep.
11:34 "Structured" vs. "dead" water, and why simply drinking enough may not be the whole hydration story.
20:40 What drinking from plastic every day could be exposing you to, and how realistic it is to avoid microplastics.
25:32 Can light, minerals, vortexing, and water-structuring devices actually change the water you drink?
46:11 Why the water in your shaker could change how your pre-workout, electrolytes, carbs, and supplements perform.
49:24 What hydration has to do with brain fog, memory, mental performance, inflammation, and energy.
58:24 Hydrogen water, fat loss, water retention, sodium, creatine, and the peak-week water mistakes that can ruin your final look.
If you train hard, take supplements, care about recovery, or simply drink litres of water every day, this episode will make you look at what is in your bottle very differently.
To receive my free book, A Guide to Biohacking, leave an honest review on the platform where you listen to the podcast, then email a screenshot to info@krisgethin.com
If you train hard, care about recovery, and want to see the tools, supplements, and products I personally recommend, head to krisgethin.com/pages/recommendations
Thank You to Our Sponsors!
Structured Water by Natural Action: Want to upgrade the quality of the water you drink every day? Head to naturalaction.com and use code KRIS at checkout.
Hydrogen Rich Water: Want an easy way to add molecular hydrogen to your hydration routine? Head to drinkhrw.com/pages/h2-in-sports and use code GETHIN for 10% off.
Find More From Kris Gethin:
Website: krisgethin.com/
Instagram: @krisgethin/
YouTube: youtube.com/krisgethin
2 Shred: unmatchedsupps.com/products/2shred
Find Out More About Alex Kikel:
Website: theprepcoach.com/
Instagram:@alex_kikel
YouTube: @alexkikelTPC
TPC Army: skool.com/tpcarmy/about- As we age, our bodies change — and so should our approach to training. In this episode, Kris Gethin shares his journey from competitive bodybuilding to a more functional, sustainable fitness routine as he navigates his 50s. He breaks down his current training split, why recovery now drives his results more than volume ever did, and how he stays mentally locked in even as the workouts themselves have changed.
What You'll Learn
Why Kris moved away from six-day, heavy-lifting training as he entered his 50s
How his goals shifted from pure muscle-building to functionality and long-term health
The training split he follows now, and why fewer days doesn't mean less intensity
What actually drives hypertrophy at this stage of life (hint: it's not more volume)
How he approaches sleep, stress, and nutrition to support recovery
Why seeking out discomfort is still central to his mindset, even with a lighter schedule
Chapters
00:00 Introduction and Kris Gethin's background
01:53 Training in his 30s and 40s versus now at 50
04:12 His current workout split and modifications
06:05 Impact of aging on recovery and joint health
07:57 The role of hormonal health and lifestyle factors
09:51 Changes in diet and supplementation over the years
12:12 Maintaining mental intensity and motivation
14:04 Making workouts more challenging and functional
15:52 Final thoughts and advice for aging athletes
Resources
FightCamp — An interactive at-home boxing and kickboxing training system with expert-led workouts, equipment, and performance-tracking technology. I often use this as my functional workout on non-training days
Code: GETHIN10 — 10% off your order
Better Bodies / GASP — Performance-focused gym apparel and training gear that I have been wearing since 2005 - designed for serious lifters.
Code: KRIS15 — 15% off your order
Bahé Trainers — Comfortable running, training and hiking shoes featuring grounding/earthing technology designed to create an electrical connection with the earth.
Code: KRIS15 — 15% off your order
Nutrition Solutions — Prepared grass fed, humane raised, organic and antibiotic free meal solutions that make it easier to stay consistent with your nutrition when life gets busy. I have used them weekly since 2015
Code: LEGACY20 for your discount
Find More From Kris Gethin
Website: krisgethin.com/
Instagram: @krisgethin/
YouTube: youtube.com/krisgethin
Tik Tok: @krisgethin - The peptide space is moving so fast that by the time a compound starts blowing up online, there is already something newer coming behind it. If you care about performance, recovery, body composition, hormones, or longevity, you need to know where this field is heading before the next wave of protocols and opinions hits your feed. Knowing what people are experimenting with now gives you a much better chance of separating something worth watching from another compound getting hyped to hell.
In this episode, Alex Kikel and I get into the new peptides, small molecules, and therapies starting to push this space forward. We talk about what is developing around mitochondria and endogenous hormone production, why Klotho is getting more attention, how far this conversation is moving beyond traditional peptides, and several compounds that could be names you hear a hell of a lot more about over the next few years.
Alex has spent roughly a decade studying and applying peptides, small molecules, bioregulators, and emerging compounds through his own experimentation and work with clients. His background also includes relationships with professionals connected to Eli Lilly and Pfizer, independent chemical synthesizers, consulting work on experimental compounds, and years of hands-on protocol development.
What's Discussed:
(00:00) Where the peptide industry is heading and the compounds starting to come down the pipeline.
(00:57) S-Mitochonic Acid 5-Ethyl Ester and why mitochondrial function is becoming such a major target.
(07:36) Phoenixin-20, neurological signaling, and endogenous hormone production.
(10:19) How Phoenixin-20 compares with enclomiphene, HCG, HMG, and kisspeptin.
(13:03) Klotho, recombinant Klotho, peptide forms, gene therapy, and why it is getting so much attention in longevity.
(21:46) Plasma exchange, EBOO, ozone, and young plasma.
(28:27) HDAP2, why Alex believes it could move beyond SS-31, and what happens when the dose is too much for the individual.
As usual, this episode is for education only. Some of what we discuss is still experimental, investigational, or needs proper medical supervision, so do your homework before you start playing with any of it.
To receive my free book, A Guide to Biohacking, leave an honest review on the platform where you listen to the podcast, then email a screenshot to info@krisgethin.com.
Find More From Kris Gethin
Website: krisgethin.com/
Instagram: @krisgethin/
YouTube: youtube.com/krisgethin
2 Shred: unmatchedsupps.com/products/2shred
Find Out More About Alex Kikel
Website: theprepcoach.com/
Instagram:@alex_kikel
YouTube: @alexkikelTPC
TPC Army: skool.com/tpcarmy/about - With more than 30 years of experience in the fitness and supplement industry, Kris Gethin breaks down which supplements are actually worth your money—and which ones may be more marketing hype than substance.
In this episode, Kris shares his take on some of the most overrated and underrated supplements on the market, what he personally looks for when evaluating a product, and why popularity doesn't always equal effectiveness. He also dives into supplement quality, formulation, ingredients, dosing, marketing claims, and some of the common mistakes consumers make when deciding what deserves a place in their daily stack.
Whether you're spending hundreds of dollars a month on supplements or just trying to figure out where to start, this episode will help you cut through the noise, question the marketing, and make more informed decisions about what's actually worth your money.
Chapters
00:00 Introduction and overview of supplement industry
01:52 Kris Gethin's background and experience in supplements
03:47 The underrated value of glutamine for healing and gut health
06:05 Chitosan and its questionable effectiveness
06:33 The underrated role of EAAs in fasting and recovery
07:03 Apple cider vinegar gummies: overrated and overpriced
08:00 Peptide 185 and its impact on recovery
08:50 Summary of overrated and underrated supplements
10:12 How marketing influences supplement perception
11:11 Final thoughts and advice for consumers
Find More From Kris Gethin
Website: krisgethin.com/
Instagram: @krisgethin/
YouTube: youtube.com/krisgethin
Tik Tok: @krisgethin
Resources
Kris's preferred peps: www.novaprimelabs.com (use code KRIS15)
Join Kris's peptide education community: www.biohackedaf.com
Kris's preferred Creatine, Fermented Glutamine, and Dileucine Peptide 185 supplements: www.unmatchedsupps.com (use code KGC10)
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About The Kris Gethin Podcast
Kris Gethin is widely known across the health and fitness space as one of the leading body transformation specialists in the world - he has been voted as the worlds #1 transformation coach and personal trainer on various platforms such as Trainerize and Bodybuilding.com and governing bodies such as PT Academy.
As the co-founder of the Kris Gethin Gyms franchise, co-founder of Unmatched Supplements, co-founder of NovaPrime Labs, founder of Biohacked AF, former editor-in-chief of BodyBuilding.com, former editor-at-large at Weider Publications and former publisher of Kaged Muscle magazine, Kris has helped educate and change the lives of millions of people. Kris is the host of The Kris Gethin Podcast and author of the best-selling book Body by Design. Kris has competed as a natural pro bodybuilder, IRONMAN Triathlete, Ultramarathoner, Spartan competitor and Motocross racer of 13 years.
He currently helps celebrities several months of the year, trains clients online year round via www.krisgethin.com and hosts anti-aging/fitness and biohacking seminars and retreats worldwide.
In this podcast, Kris dissects myths of muscle building and endurance, bridges the gap between health and sports supplementation, expands upon the healing benefits of smart nutrition, and strategies to change your perception for a happier, healthier and real way of life.
For more information check out https://www.krisgethin.com/
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