Messari's Unqualified Opinions

In this episode, Sami and Seth break down why crypto + AI isn’t just a moral counterweight to Big Tech—it’s a faster innovation engine. They explain how BitTensor’s subnet model turns AI development into an open, incentive-driven competition (similar to how Bitcoin relentlessly optimized SHA-256), and why 2025’s biggest shifts—open-source catching up, reinforcement learning’s rise, and massive data center capex—set the stage for decentralized AI to find real product-market fit. The conversation also digs into value accrual, why buybacks can be a trap, and which crypto-AI sectors could surprise people in 2026 (agents, privacy, robotics, and GPU financing).📘 Read the full (free) Crypto Theses 2026 report: https://messari.io/report/the-crypto-theses-20260:00 AI & DePIN Trends10:28 Training Subnet14:07 Investing Approach20:25 Revenue Growth22:35 Token Strategy40:26 Compute & Infra41:59 Future OutlookHosted by Chris Davis of MessariSubscribe for more conversations at the intersection of crypto, DePIN, and real-world infra.Follow Messari on Twitter: https://twitter.com/MessariCryptoFollow Unqualified Opinions on Spotify: https://open.spotify.com/show/0uG5qpwFg67zTt0VQRTaZ7?si=13163cbebe01415eFollow Unqualified Opinions on Apple Podcasts: https://podcasts.apple.com/us/podcast/messaris-unqualified-opinions/id1455666979____This episode and its contents do not necessarily reflect the opinions of Messari, Inc. Hosts and guests may hold cryptocurrencies discussed in this content. This content is meant for informational purposes only. It is not meant to serve as investment advice. You should conduct your own research, and consult an independent financial, tax, or legal advisor before making any investment decisions. Nothing contained in this content is a recommendation or suggestion, directly or indirectly, to buy, sell, make, or hold any investment, loan, commodity, or security, or to undertake any investment or trading strategy with respect to any investment, loan, commodity, security, or any issuer. This content should not be construed as an offer to sell or the solicitation of an offer to buy any security or commodity. Messari does not guarantee the sequence, accuracy, completeness, or timeliness of any information provided in this content.

In this episode, Sami and Seth break down why crypto + AI isn’t just a moral counterweight to Big Tech—it’s a faster innovation engine. They explain how BitTensor’s subnet model turns AI development into an open, incentive-driven competition (similar to how Bitcoin relentlessly optimized SHA-256), and why 2025’s biggest shifts—open-source catching up, reinforcement learning’s rise, and massive data center capex—set the stage for decentralized AI to find real product-market fit. The conversation also digs into value accrual, why buybacks can be a trap, and which crypto-AI sectors could surprise people in 2026 (agents, privacy, robotics, and GPU financing).📘 Read the full (free) Crypto Theses 2026 report: https://messari.io/report/the-crypto-theses-20260:00 AI & DePIN Trends10:28 Training Subnets14:07 Investing Approach20:25 Revenue Growth22:35 Token Strategy40:26 Compute & Infra41:59 Future OutlookHosted by Chris Davis of MessariSubscribe for more conversations at the intersection of crypto, DePIN, and real-world infra.Follow Messari on Twitter: https://twitter.com/MessariCryptoFollow Unqualified Opinions on Spotify: https://open.spotify.com/show/0uG5qpwFg67zTt0VQRTaZ7?si=13163cbebe01415eFollow Unqualified Opinions on Apple Podcasts: https://podcasts.apple.com/us/podcast/messaris-unqualified-opinions/id1455666979____This episode and its contents do not necessarily reflect the opinions of Messari, Inc. Hosts and guests may hold cryptocurrencies discussed in this content. This content is meant for informational purposes only. It is not meant to serve as investment advice. You should conduct your own research, and consult an independent financial, tax, or legal advisor before making any investment decisions. Nothing contained in this content is a recommendation or suggestion, directly or indirectly, to buy, sell, make, or hold any investment, loan, commodity, or security, or to undertake any investment or trading strategy with respect to any investment, loan, commodity, security, or any issuer. This content should not be construed as an offer to sell or the solicitation of an offer to buy any security or commodity. Messari does not guarantee the sequence, accuracy, completeness, or timeliness of any information provided in this content.

Messari’s Theses 2026 multi-chain roundtable breaks down who’s really winning the L1 / L2 wars and what that means for the next cycle.The Enterprise team dives into:- How Ethereum clawed back from peak despair in 2025- Why Arbitrum and Base are pulling away from the L2 pack- What a Robinhood L2 could mean for every existing rollup- MegaETH’s token + native stablecoin experiments- Jeremy’s new Disruption Factor framework for ranking L2s- Solana’s push to become the “onchain NASDAQ”- Hot takes for 2026: Starknet, Monad, native stablecoins, and moreWatch alongside Messari Crypto Theses 2026 for the full data-driven breakdown of L1, L2, and multichain trends. 📘 Read the full report: https://messari.io/report/the-crypto-theses-20260:00 Ethereum Outlook5:41 Ethereum Scaling7:17 Ethereum Narrative16:45 Robinhood Chain25:09 Base & L2s35:33 L2 Research41:18 Solana Outlook51:12 L1 InnovationHosted by Patryk Krasnicki of MessariSubscribe for more conversations at the intersection of crypto, DePIN, and real-world infra.Follow Messari on Twitter: https://twitter.com/MessariCryptoFollow Unqualified Opinions on Spotify: https://open.spotify.com/show/0uG5qpwFg67zTt0VQRTaZ7?si=13163cbebe01415eFollow Unqualified Opinions on Apple Podcasts: https://podcasts.apple.com/us/podcast/messaris-unqualified-opinions/id1455666979____This episode and its contents do not necessarily reflect the opinions of Messari, Inc. Hosts and guests may hold cryptocurrencies discussed in this content. This content is meant for informational purposes only. It is not meant to serve as investment advice. You should conduct your own research, and consult an independent financial, tax, or legal advisor before making any investment decisions. Nothing contained in this content is a recommendation or suggestion, directly or indirectly, to buy, sell, make, or hold any investment, loan, commodity, or security, or to undertake any investment or trading strategy with respect to any investment, loan, commodity, security, or any issuer. This content should not be construed as an offer to sell or the solicitation of an offer to buy any security or commodity. Messari does not guarantee the sequence, accuracy, completeness, or timeliness of any information provided in this content.

In this episode of the Messari Thesis Podcast, the Enterprise research team recaps the wild year that was 2025 and lays out their highest-conviction bets for 2026. We dig into why Bitcoin has clearly separated from the rest of the market, how Hyperliquid and a handful of standout apps stole the spotlight, and why long-tail L1s are running out of room. The team debates whether institutions really break the four-year cycle, how the stablecoin and yield meta evolves as rates fall, and where DeFi banks, RWAs, and prediction markets actually fit.We also get into L1 vs L2 dynamics, Solana’s on-chain market structure experiments, the rise of yield-generating stablecoins, and the explosion of on-chain derivatives from equity perps to exotic real-world assets. Finally, everyone shares one spicy prediction for 2026—from a G20 nation adding Bitcoin to its strategic reserves to a single meme coin rising from the ashes.00:00 2025 Winners & Losers07:00 L1, L2 & Multichain09:25 Institutions & Stablecoins13:55 Yield & DeFi Banks23:45 2026 Narratives28:55 Regulation & Tokens33:30 Equity Perps & TradFi40:10 2026 Market OutlookHosted by Matthew Nay of MessariSubscribe for more conversations at the intersection of crypto, DePIN, and real-world infra.Follow Messari on Twitter: https://twitter.com/MessariCryptoFollow Unqualified Opinions on Spotify: https://open.spotify.com/show/0uG5qpwFg67zTt0VQRTaZ7?si=13163cbebe01415eFollow Unqualified Opinions on Apple Podcasts: https://podcasts.apple.com/us/podcast/messaris-unqualified-opinions/id1455666979____This episode and its contents do not necessarily reflect the opinions of Messari, Inc. Hosts and guests may hold cryptocurrencies discussed in this content. This content is meant for informational purposes only. It is not meant to serve as investment advice. You should conduct your own research, and consult an independent financial, tax, or legal advisor before making any investment decisions. Nothing contained in this content is a recommendation or suggestion, directly or indirectly, to buy, sell, make, or hold any investment, loan, commodity, or security, or to undertake any investment or trading strategy with respect to any investment, loan, commodity, security, or any issuer. This content should not be construed as an offer to sell or the solicitation of an offer to buy any security or commodity. Messari does not guarantee the sequence, accuracy, completeness, or timeliness of any information provided in this content.

How much of “crypto AI” is still just narrative—and how much is finally real?In this episode, Messari’s Enterprise team unpacks findings from Messari’s newly released State of AI Report and what they mean for decentralized AI, infra, and the broader market. Chris walks through why post-training, reinforcement learning, and test-time compute are pushing us into a new decentralized AI paradigm, from swarm-style inference networks like 42 Network to open source models that are finally seeing real, paid demand.Read the Full State of AI 2025 for FREE: https://messari.io/report/state-of-ai00:00 – Introductions01:11 – State of AI & Crypto08:28 – AI Agents & Micropayments23:05 – New L1 & TG Analysis36:10 – Market & Cycle Outlook50:04 – Token Launch Advice56:22 – On-Chain Activity57:52 – ConclusionHosted by Matthew Nay of MessariSubscribe for more conversations at the intersection of crypto, DePIN, and real-world infra.Follow Messari on Twitter: https://twitter.com/MessariCryptoFollow Unqualified Opinions on Spotify: https://open.spotify.com/show/0uG5qpwFg67zTt0VQRTaZ7?si=13163cbebe01415eFollow Unqualified Opinions on Apple Podcasts: https://podcasts.apple.com/us/podcast/messaris-unqualified-opinions/id1455666979____This episode and its contents do not necessarily reflect the opinions of Messari, Inc. Hosts and guests may hold cryptocurrencies discussed in this content. This content is meant for informational purposes only. It is not meant to serve as investment advice. You should conduct your own research, and consult an independent financial, tax, or legal advisor before making any investment decisions. Nothing contained in this content is a recommendation or suggestion, directly or indirectly, to buy, sell, make, or hold any investment, loan, commodity, or security, or to undertake any investment or trading strategy with respect to any investment, loan, commodity, security, or any issuer. This content should not be construed as an offer to sell or the solicitation of an offer to buy any security or commodity. Messari does not guarantee the sequence, accuracy, completeness, or timeliness of any information provided in this content.