On with Kara Swisher

Comedian Nikki Glaser’s star is on the rise. The two-time host of the Golden Globe Awards is set to take the mic for a third straight year in 2027. Glaser was also just named one of Time magazine’s most influential people of the year. And on Friday, Hulu is releasing her latest hour-long comedy special, “Good Girl.” It’s an exploration of aging, fame, and sexuality in Glaser’s signature raw and self-deprecating style. 

Kara and Nikki talk about why she thinks it's wrong to shame women who spend money on their appearance and why talking about sex is still a big part of her comedy. They also discuss why she shies away from making political jokes right now and what it’s like to have her breakout moment in her 40s. 

Questions? Comments? Email us at [email protected] or find us on YouTube, Instagram, TikTok, Threads, and Bluesky @onwithkaraswisher.
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Pulitzer Prize-winning New York Times investigative reporter Jodi Kantor joins Kara to talk about her new book, “How to Start: Discovering Your Life’s Work.” It’s a guide for young people starting their careers in an age of AI disruption, economic instability and political chaos. 

Jodi acknowledges the difficult reality graduates face and tries to offer practical yet empathic advice. She argues that meaningful careers are built on “craft” and “need.” Kara and Jodi discuss how to find workarounds in an automated hiring hellscape, and what key things to look for in a first job. Plus, Jodi explains why young people need to take calculated risks, and what that looks like for recent graduates. 

Questions? Comments? Email us at [email protected] or find us on YouTube, Instagram, TikTok, Threads, and Bluesky @onwithkaraswisher.

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On the heels of the weekend premiere of her new CNN series, “Kara Swisher Wants To Live Forever,” Kara brings together a panel of experts to talk more about longevity, anti-aging, and the money that’s pouring into the wellness industry.

Katie Couric is a journalist. She’s also been a longtime advocate for early cancer screenings since her first husband died of colon cancer and she was diagnosed with breast cancer. 

Amy Larocca is an award-winning journalist and author of the book, “How To Be Well: Navigating Our Self-Care Epidemic, One Dubious Cure At A Time.” 

And Kara’s brother, Dr. Jeffrey Swisher, is chairman of the Department of Anesthesiology at California Pacific Medical Center in San Francisco. He recently caught a so-called “widowmaker” heart attack before it happened, and his wife has also been diagnosed with stage 3 colon cancer.

Kara, Katie, Amy and Jeff talk about the explosion of health misinformation online and why people have become so skeptical of medical experts. They also talk about the promising health care science on the horizon and the real secrets to living a long, happy life. 

Questions? Comments? Email us at [email protected] or find us on YouTube, Instagram, TikTok, Threads, and Bluesky @onwithkaraswisher.
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Dr. Eric Topol, the founder and director of the Scripps Research Translational Institute, joins Kara to discuss reality versus the hype in the booming longevity business ahead of her new CNN series "Kara Swisher Wants to Live Forever." 

Dr. Topol has written several books, including his latest, "Super Agers: An Evidence-Based Approach to Longevity," which explores the science behind anti-aging and longevity. He explains why the biggest breakthroughs in aging science focus not on extending lifespan, but on extending health span and preventing the chronic diseases that affect most Americans over 65. And Topol takes aim at the “longevity lifespan circus” of pricey supplements and peptides sold by wellness grifters. Kara and Dr. Topol also talk about how inequality, poverty and the lack of universal healthcare in the US impact health span, and what can be done about it. 

Questions? Comments? Email us at [email protected] or find us on YouTube, Instagram, TikTok, Threads, and Bluesky @onwithkaraswisher.
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Kara’s 2023 interview with journalist and biographer Walter Isaacson about his Elon Musk biography was one of her most contentious conversations ever — and one of the show’s most popular episodes. They’re still friends, though. And at this year’s New Orleans Book Festival at Tulane University, Isaacson got his chance to put Kara in the hot seat.

In this live conversation, recorded last month, Kara and Isaacson talk about the future of A.I., how power is shifting in the United States, and how those changes are reshaping American life. They also talk about Kara’s new CNN series, “Kara Swisher Wants to Live Forever.” 

Special thanks to the New Orleans Book Festival for hosting this event. 

Questions? Comments? Email us at [email protected] or find us on YouTube, Instagram, TikTok, Threads, and Bluesky @onwithkaraswisher.
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