Taking too many supplements with vitamin B6 in them can lead to concerning symptoms and even long-term nerve pain. Now, more concerns are being raised about B6-containing products, this time energy drinks that contain far more than the daily recommended amount. Also, a new study estimates the lives and life-years saved by COVID-19 vaccination — and another study assesses the safety of updated mRNA vaccines. ReferencesGlobal Estimates of Lives and Life-Years Saved by COVID-19 Vaccination During 2020-2024 | Health Policy | JAMA Health Forum | JAMA NetworkSafety of JN.1-Updated mRNA COVID-19 Vaccines | Pharmacy and Clinical Pharmacology | JAMA Network Open | JAMA Network
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Ultraprocessed or not? It matters when following dietary guidelines
A diet full of ultraprocessed foods (UPFs) has generally been thought to be bad for your health – and a trigger for disease.But for the first time a study has looked at the health effects of UPFs within the context of national dietary guidelines.And while a minimally processed diet is still better for you overall, it’s not all bad news if you’re sticking close to those directions.Guest/sDr Sam Dicken, Centre for Obesity Research, University College LondonReferencesUltraprocessed or minimally processed diets following healthy dietary guidelines on weight and cardiometabolic health: a randomized, crossover trial
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Should we change how we're diagnosing perimenopause?
It can be hard to know when a woman is in perimenopause, which is the transitional phase leading up to menopause.In the past irregular periods were thought to be one of the first indicators of fluctuating hormones.But vasomotor symptoms – like hot flashes and night sweats – are also reliable indicators, especially for women who already have inconsistent menstrual cycles.Guest/sProfessor Susan Davis, director of the Monash University Women’s Health Research Program and head of the Women’s Endocrine Clinic, Alfred Hospital Melbourne ReferencesPrevalence and severity of symptoms across the menopause transition: cross-sectional findings from the Australian Women's Midlife Years (AMY) Study
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Has psilocybin's depression benefit been overestimated?
Psilocybin, a psychoactive compound found in magic mushrooms, is approved in Australia for use in treatment-resistant depression.But a new study suggests the benefits of psilocybin in these patients might not be as effective as past clinical trials have suggested.In 2023, Australia became the first country in the world to legalise the use of psychedelics to treat some mental health conditions.Guest/sAssociate Professor Fredrik Hieronymus, Group leader of the clinical psychopharmacology group, University of GottenburgReferencesControl Group Outcomes in Trials of Psilocybin, SSRIs, or Esketamine for Depression
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Mailbag: Coordinating care
A look at some of the Health Report correspondence this week.You can email us at [email protected]