PodcastsBusinessThe a16z Show

The a16z Show

Andreessen Horowitz
The a16z Show
Latest episode

1032 episodes

  • The a16z Show

    AI’s Capital Flywheel: Models, Money, and the Future of Power

    19/02/2026 | 57 mins.
    a16z's Martin Casado and Sarah Wang join Latent Space hosts Alessio Fanelli and Swyx to discuss what makes this AI investment cycle unlike anything in the history of venture capital. They cover why the lines between venture and growth, apps and infrastructure are blurring, how frontier model companies can raise more than the aggregate of everyone built on top of them, and why the industry-wide gap between perception and reality has never been wider.

    Follow Alessio Fanelli on X: https://x.com/FanaHOVA

    Follow Swyx (Shawn Wang) on X: https://twitter.com/FanaHOVA

    Follow Martin Casado on X: https://twitter.com/martin_casado

    Follow Sarah Wang on X: https://twitter.com/sarahdingwang  

    Listen to more from Latent Space: https://www.youtube.com/@LatentSpacePod

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    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
  • The a16z Show

    From Copilots to Agents: Rebuilding the Company Around AI

    18/02/2026 | 59 mins.
    a16z's Angela Strange and Gabriel Vasquez speak with Carlos García Ottati, founder and CEO of Kavak, about building Latin America's largest online used car marketplace across Mexico, Brazil, Chile, Argentina, and the Middle East. They discuss why building in emerging markets means constructing four businesses underneath your business, how Kavak replaced copilot tools with AI agents handling 90 to 95% of customer interactions, and what it took to go flat for a year during the transition before growing four times on the other side.
     
     

    Stay Updated:
    Find a16z on YouTube: YouTube
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    Find a16z on LinkedIn
    Listen to the a16z Show on Spotify
    Listen to the a16z Show on Apple Podcasts
    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
  • The a16z Show

    WSJ x a16z: The Next 25 Years of Defense Innovation

    17/02/2026 | 30 mins.
    In this episode from WSJ Invest Live, Andy Serwer speaks with Katherine Boyle, general partner at a16z, about the American Dynamism practice she helped launch four years ago. They discuss why saying "America" out loud stunned Silicon Valley in 2022, how Russia's invasion of Ukraine changed everything, and what it means to invest in companies that support the national interest.
     
     

    Stay Updated:
    Find a16z on YouTube: YouTube
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    Find a16z on LinkedIn
    Listen to the a16z Show on Spotify
    Listen to the a16z Show on Apple Podcasts
    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
  • The a16z Show

    Novartis CEO Vasant Narasimhan on Transforming a 250-Year-Old Company

    16/02/2026 | 58 mins.
    a16z general partner Jorge Conde talks with Vasant Narasimhan, CEO of Novartis International, about transforming a 250-year-old conglomerate into a pure play medicines company and unlocking $180 billion of value in the process. They cover Novartis's platform technologies: cell and gene therapies, RNA medicines, and radioligand therapies. They also discuss AI in drug discovery, the rise of China as a biotech competitor, and what Vasant looks for when evaluating startup partnerships, including his advice on the killer experiments and CMC work that can make or break a deal.
     
    Resources: 
    Follow Vasant Narasimhan on LinkedIn: https://www.linkedin.com/in/vasnarasimhan/
    Follow Jorge Conde on X: https://x.com/JorgeCondeBio
     

    Stay Updated:
    Find a16z on YouTube: YouTube
    Find a16z on X
    Find a16z on LinkedIn
    Listen to the a16z Show on Spotify
    Listen to the a16z Show on Apple Podcasts
    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
  • The a16z Show

    Balaji and Dan Wang: The Engineering State vs Lawyerly State

    13/02/2026 | 1h 3 mins.
    Balaji Srinivasan speaks with Dan Wang, author of Breakneck, about China's industrial rise, America's competing strengths in software and finance, and what happens when an engineering state and a lawyerly state collide. The conversation covers manufacturing dominance, the future of the dollar, why both superpowers keep making costly mistakes, and where builders fit into what comes next.
     
    Resources:
    Follow Dan Wang on X: https://twitter.com/danwwang
    Follow Balaji on X: https://twitter.com/balajis
    Subscribe to Network State Podcast:  https://www.youtube.com/@nspodcast

    Stay Updated:
    Find a16z on YouTube: YouTube
    Find a16z on X
    Find a16z on LinkedIn
    Listen to the a16z Show on Spotify
    Listen to the a16z Show on Apple Podcasts
    Follow our host: https://twitter.com/eriktorenberg

    Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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About The a16z Show

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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