The Human Upgrade with Dave Asprey

• This Is Your Brain on 2025: The Biohacker’s Guide to Mental Clarity & Mood | Dr. Drew Ramsey : 1263

  You think you’re optimizing your brain—but what if the real culprit behind your brain fog, anxiety, and burnout is the modern world itself? In this episode, Columbia University psychiatrist and nutritional neuroscience pioneer Dr. Drew Ramsey joins Dave Asprey to decode the biological chaos hijacking your mind—and how to fight back. From inflammation and gut dysbiosis to screen-induced disconnection and hidden trauma, this is the ultimate roadmap for healing the modern brain. You’ll explore the cutting-edge science of neuroplasticity, discover how movement and social connection trigger brain growth, and learn why food is still your most powerful antidepressant. Plus: dancing, psychedelics, kale debates, and why porn is quietly reshaping the male brain. What You’ll Discover in This Episode: • Why brain fog, anxiety, and mood swings might be signs your brain is inflamed • How movement—especially dancing—can literally help your brain grow stronger • What your gut has to do with your mental health (and why some “healthy” foods can backfire) • The truth about antidepressants, supplements, and why there’s no one-size-fits-all fix • Why porn, ultra-processed food, and doomscrolling are silently wrecking focus and drive • A new way to think about mental fitness—like a workout plan for your brain SPONSORS -BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 for 20% off your first order of PerfectAmino. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • A Day of Biohacking and Consciousness Event April 12th: https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Drew’s Instagram: https://www.instagram.com/drewramseymd/?hl=en • Drew’s Linktree: https://shorturl.at/CIIR5 • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 01:43 – Intro • 02:51 – The State of Mental Health Today • 04:00 – Nutritional Psychiatry and Personal Experiences • 05:21 – Environmental Factors and Brain Health • 05:55 – Chemical Balance and Psychiatry • 09:19 – Mental Fitness and Connection • 14:17 – Modern Brain Challenges • 16:26 – The Role of Movement and Dance • 22:44 – Sex, Relationships, and Mental Health • 34:02 – Microbiome and Mental Health • 36:50 – Transitioning to Urban Life and Mental Health • 37:29 – The Role of Nature in Mental Well-being • 38:14 – Personal Experiences with Gut Health • 39:45 – Trial and Error in Mental Health • 42:16 – Cognitive Resilience and High Performance • 45:37 – The Importance of Family Meals • 46:33 – Challenges of Rural and Urban Living • 47:53 – Brain Health: Beyond Neurons • 49:01 – Neuroplasticity and Mental Fitness • 52:50 – Biohacking Mental Health • 57:31 – The Role of Serotonin in Depression • 01:03:57 – Debating the Benefits of Kale • 01:12:03 – Final Thoughts on Mental Health and Resilience See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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  1:11:07
• The Science of Consciousness: What’s Beyond the Brain? | Mark Gober : 1262

  You think, you feel, you are—but what if your consciousness isn’t just in your brain? What if reality itself is shaped by something beyond the physical? In this episode, Mark Gober—author, consciousness researcher, and former Silicon Valley banker—joins Dave Asprey to challenge everything you think you know about the mind, reality, and human potential. He explores groundbreaking research on near-death experiences, psychic phenomena, and why some scientists believe consciousness may exist beyond the body. Mark reveals how declassified CIA documents, quantum physics, and meditation practices point to a deeper, more interconnected world—one where perception creates reality. If you’ve ever questioned whether free will is an illusion, wondered about life after death, or wanted to tap into higher states of awareness, this episode will shift your perspective. What You’ll Discover in This Episode: • Is consciousness non-local? Why your brain might not be the source of your thoughts • Near-death experiences & life after death—the science and firsthand accounts • Psychic phenomena & remote viewing—what the CIA doesn’t want you to ignore • Float tanks, meditation & altered states—how to access expanded awareness • The AI consciousness debate—can machines ever become truly self-aware? • Protecting your energy—why spiritual safeguards matter when exploring altered states SPONSORS -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • A Day of Biohacking and Consciousness Event April 12th: https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Mark’s Instagram: https://www.instagram.com/markgober_author/ • Mark’s Website: https://www.markgober.com/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: 00:00 - Trailer 00:50 - Intro 03:11 - Meet Mark Gober 05:25 - From Banking to Awakening 10:16 - Float Tanks & Consciousness 12:35 - Psychic Phenomena 19:14 - Science & Skepticism 25:51 - Personal Experiences 40:51 - Spiritual Protection 42:58 - Parasitic Entities 44:59 - Psychedelics & Mindset 45:58 - Alien Abductions 47:04 - Navigating Psychedelics 51:58 - Intuition & Inner Knowing 58:41 - Telepathy & Remote Viewing 59:46 - Near-Death Experiences 01:04:54 - Consciousness Beyond the Brain 01:12:38 - Psychic Abilities & Ethics 01:24:11 - Consciousness & Reality 01:27:58 - Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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  1:27:52
• The Hidden Cost of Being Too Nice: Why People-Pleasing is Silently Killing Your Success | Scott Barry Kaufman : 1261

  You hold the door open. You say yes when you mean no. You put others first—always. It feels like the right thing to do… but is it costing you more than you realize? In this episode, Scott Barry Kaufman, Ph.D.—Columbia professor, psychologist, and author of Rise Above—joins Dave Asprey to expose the psychology of victim vs. empowerment mindsets. He reveals how toxic altruism, external validation, and emotional fragility keep people stuck—and how you can reclaim your confidence, set boundaries, and create a life of true growth. Dr. Kaufman, one of the world’s most cited scientists, shares cutting-edge research on self-actualization, resilience, and the hidden mental loops that shape your success. If you’ve ever felt stuck in self-doubt, drained from over-giving, or afraid to take up space, this conversation will help you break free. What You’ll Discover in This Episode: • Victim vs. empowerment mindset—the key shift that changes everything • The psychological traps of toxic altruism—and why over-giving holds you back • How people-pleasing rewires your brain—and how to break the cycle • The science of self-actualization—how to unlock your full potential without guilt • Why modern culture and social media reward emotional fragility—and how to rise above it • The neuroscience behind confidence, resilience, and making better choices for YOUR growth If you’ve ever felt stuck, undervalued, or drained from always being “nice”, this episode will show you how to step into your power, rewrite your mental programming, and take control of your future. SPONSORS -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Resources: • A Day of Biohacking and Consciousness Event: https://daveasprey.com/biohacking-and-consciousness/ • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Scott’s Instagram: https://www.instagram.com/scottbarrykaufman/?hl=en • Scott's New Book – Rise Above:https://scottbarrykaufman.com/books/rise-above/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 Trailer • 00:44 Intro • 02:02 Rise Above – Scott’s New Book • 03:13 Triggers and Mind Control • 05:12 Victimhood and Self-Actualization • 12:01 Curiosity Over Fear • 16:32 The Power of Discernment • 26:32 Emotional Resilience Today • 31:12 The Fragility of Younger Generations • 37:33 Social Pressures and Identity • 39:47 Social Media and Self-Determination • 40:35 Community and Belonging • 42:42 Activating Happiness and Growth • 44:43 Gratitude and Daily Practices • 51:48 Healthy Selfishness vs. Altruism • 58:56 Codependency and Vulnerable Narcissism • 01:04:57 The Dark Triad and Personality Types • 01:09:14 Final Thoughts and Book Recs See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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  1:14:46
• MDMA Therapy Without the Drugs? How Vibration Hacks Your Brain for Neuroplasticity | Dave Rabin : 1260

  What do vibrations and the psychedelic experience have in common? MDMA therapy is revolutionizing mental health treatment, helping people overcome PTSD, anxiety, and emotional trauma with unprecedented success. But what if you could tap into those same powerful benefits—without taking a single drug? It turns out your brain responds to more than just chemistry. Vibration, frequency, and rhythm have been shaping human consciousness for millennia—from ancient chanting rituals to modern neuroscience breakthroughs. Could the right vibrations unlock the same neuroplasticity and healing pathways as psychedelics? In this episode, Dave Asprey sits down with Dr. Dave Rabin, a neuroscientist, psychiatrist, and psychedelic researcher, to explore how vibrations can rewire your brain, enhance neuroplasticity, and even mimic the effects of MDMA therapy. Dr. Rabin’s work led to the creation of Apollo Neuro, a wearable device that taps into your nervous system’s natural ability to regulate stress, boost focus, and accelerate recovery—without pharmaceuticals. What You’ll Discover in This Episode: • How specific vibrations trigger deep relaxation and neuroplasticity • Why MDMA therapy works—and how vibration-based tech can simulate it • The surprising science behind music, frequency, and altered states • How Apollo Neuro enhances sleep, focus, and emotional resilience • The overlooked role of heart rate variability in longevity and health • Why stress is the biggest obstacle to healing—and how to override it **Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%** Resources: • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Apollo Neuro Instagram: https://www.instagram.com/apolloneuro/?hl=en • Apollo Neuro Website: https://apolloneuro.com/Dave • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: 00:00 Trailer 00:40 Intro 01:18 Exploring Vibration in Biohacking 02:29 Introduction of Dr. Dave Rabin 02:53 Understanding Vibration and Its Impact 04:47 The Apollo Neuro Device 08:44 Using Apollo for Different States 11:41 Apollo in Psychedelic Therapy 24:32 Clinical Trials and Studies on Apollo 29:32 Heart Rate Variability and Biohacking 33:02 Revolutionizing Sleep with Apollo 34:40 Apollo’s Long-Term Effects and Dependency 37:16 Apollo’s Impact on ADHD and Psychiatric Disorders 45:22 The Importance of Human Connection and Simple Solutions 49:56 Longevity, Healthspan, and Future Innovations 57:23 Final Thoughts and Discount Offer See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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  58:25
• Brain Hacking 101: The Science of Self-Sabotage & Mind Reprogramming | Bizzie Gold : 1259

  Your Brain is Lying to You—Here’s How to Take Back Control Every day, your brain is running subconscious scripts—hidden mental loops that shape your decisions, habits, and even your self-worth. But what if those loops are sabotaging you? In this episode, Bizzie Gold, mind architect and creator of The Break Method, joins Dave Asprey to expose the self-deception patterns controlling your thoughts—and how to reprogram your brain for true transformation. Bizzie’s method isn’t just another self-help philosophy. It’s science-backed, no BS, and engineered for results. From subconscious conditioning to emotional addiction cycles, you’ll learn the exact framework for breaking free from limiting beliefs and upgrading your mind. What You’ll Discover in This Episode: • The hidden mental loops sabotaging your success (and how to break them) • The science of self-deception—why your brain lies to you daily • How early childhood experiences hardwire your thoughts and emotions • The brain’s rejection vs. abandonment patterns—which one rules you • How to use E.L.I. questions to disrupt negative thinking instantly • The AI-powered brain upgrade that could change self-improvement forever If you’ve ever felt stuck in repetitive thought patterns, bad habits, or emotional cycles, this episode will give you the blueprint to take back control of your mind. Listen now—because your brain won’t fix itself. SPONSORS -Omni-Biotic | Visit omnibioticlife.com/dave and use code DAVE20 for 20% off. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Bizzie Gold’s Instagram: https://www.instagram.com/bizziegold/ • Bizzie Gold's Website: https://bizziegold.com/ • Danger Coffee: https://dangercoffee.com • Dave Asprey’s Website: https://daveasprey.com • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 00:28 – Intro • 01:39 – Understanding self-deception and its impact • 05:41 – The role of childhood trauma in shaping perception • 14:20 – Brain pattern spectrum and human behavior • 22:26 – Spiritual perspectives on DNA and past lives • 34:45 – Sharing knowledge from the ether • 34:54 – A surprising encounter with a professor • 35:43 – Healing and accessing intuition • 36:39 – The power of intuition in practice • 38:15 – Spiritual technology and Big Pharma • 39:54 – The role of self-trust in intuition • 40:49 – Understanding instinct vs. intuition • 42:17 – The E.L.I. framework for intuition • 45:50 – Hacking the brain’s language system • 57:04 – Parenting for emotional resilience • 01:06:13 – AI and emotional hacking • 01:11:01 – Conclusion and final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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  1:09:58

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