Project 100 with Mark Bouris

Tim Piatowski is one of Australia's leading researchers on peptides and enhancement drugs, running the world's first steroid-checking trial and service.
In this conversation, we cover everything from what peptides actually are to the underground markets driving their use across Australia. Tim explains the science behind popular compounds like BPC-157 and GHK-Cu, the risks of unregulated products, and why Australia's regulatory approach is pushing people toward dangerous illicit markets. We also explore the potential for peptides in healthy ageing, injury recovery, and why our government's silence on this growing trend is creating more problems than solutions.
We speak about:
• What peptides are and how they work as signalling molecules
• BPC-157 for tissue healing and inflammation reduction
• GHK-Cu copper peptides for collagen synthesis and skin health
• Growth hormone releasing peptides like CJC-1295 and tesamorelin
• The contamination crisis in illicit enhancement drugs
• Legal pathways vs underground markets in Australia
• How peptides could transform healthy ageing and falls prevention
See omnystudio.com/listener for privacy information.

Maria Andriano is one of Australia's leading strength coaches whose incredible physique at 54 proves that muscle truly is the fountain of youth.
In this episode, she reveals why building and maintaining muscle mass isn't just about aesthetics—it's your first line of defence against aging, illness, and frailty.
• Why women lose 10% muscle mass every decade after 30 and how to stop it
• The five compound movements every woman should master for longevity
• Post-workout nutrition timing that actually builds muscle (not just burns calories)
• How strength training during menopause can reverse hormonal decline
• Why the Ozempic generation is setting themselves up for metabolic disaster
• Maria's exact training split for maximum muscle gain with minimal gym time
• The truth about why most people plateau after years of training

All content is for informational purposes only and is not medical advice.
See omnystudio.com/listener for privacy information.

All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice.
****
Professor Matthew Kiernan is CEO of Neura and one of the nation's leading neurologists tackling the growing dementia crisis.
Kiernan explores why dementia is now Australia's number one cause of death, the modifiable risk factors that could prevent 45% of cases, and the groundbreaking monoclonal antibody treatments now available for Alzheimer's disease.
Kiernan explains how the Western Pacific region carries 60% of the world's dementia burden and why researchers are racing to develop blood biomarkers that could detect brain diseases decades before symptoms appear. We also get into:
• Why dementia has overtaken heart disease as Australia's leading killer
• The role of vascular health in brain function and cognitive decline
• Blood biomarkers coming within five years for early detection
• Monoclonal antibody treatments for Alzheimer's now available in Australia
• The connection between contact sports, head injuries and neurodegeneration
• How GLP-1 medications are showing promise for brain health
• Sleep's critical role in clearing toxic proteins from the brain

Join my exclusive Mentored+ community: https://mentored.com.au/become-a-member/
Subscribe to the Mentored newsletter here: https://mentored.com.au/newsletter
See omnystudio.com/listener for privacy information.

All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice.
****
Professor David Heslop brings a unique perspective to longevity through his expertise in occupational medicine, military service, and biological threat assessment. From developing COVID protocols for the NRL to understanding genetic manipulation in laboratories, Heslop explores the hidden factors shaping our health future.

This conversation covers:
• Gene editing and its potential risks for future generations
• The concerning gap between wealthy and poor in accessing longevity technologies
• Australia's cautious approach to new medical testing versus other countries
• How AI will transform medical practice while protecting patient privacy
• The critical data we're missing despite drowning in health information
• Why living longer might create unexpected economic and social problems
The all-new WHOOP is here — now 7% smaller with 14+ days of battery life. New features like Healthspan show how your daily habits are affecting your rate of aging — and now you can check your blood pressure straight from your wrist. If you’re serious about performance, longevity, and actual progress — this is it. Sign up for a one-month free trial at WHOOP.com — or visit join.whoop.com/mentored for one month off your annual membership fee.
Eight Sleep’s newest generation, Pod 5. isn’t just another bed-frame add-on; it’s a high-tech mattress cover that actively adjusts to your body temperature throughout the night, cooling, warming, and even elevating your body when needed, all based on real-time data. The new Pod 5 introduces for the first time, a hydro-powered blanket system, utilising the same technology as the cover to extend temperature regulation across your entire body, not just the mattress surface. Clinically proven to increase quality sleep by up to one hour each night, it’s basically like having an AI-powered sleep coach, personal thermostat, and advanced health tracker working for you while you rest.
Head on over to eightsleep.com/project100 and use the code PROJECT100 (that’s Project one-zero-zero) and get up to $550 off your very own Pod 5. Trust me, your body will thank you for this investment in better sleep.
See omnystudio.com/listener for privacy information.

All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice.
****
Dr. Anastasia Hronis brings unique expertise to addiction psychology, exploring how modern technology is rewiring our brains for dependency.
Her surname literally means "long years" — fitting for a conversation about optimising our relationship with dopamine-driven behaviours for longevity.
We spoke about:
• Understanding addiction versus obsession: the neurological differences
• How dopamine pathways become primed for unhealthy patterns
• Why poker machines and social media apps use identical addiction mechanics
• The critical role of frustration tolerance in building resilience
• Why today's youth face unprecedented challenges to mental wellbeing
• Practical strategies for "prescribed boredom" and digital detox
• The alarming parallels between gambling platforms and social media design

This conversation reveals how our convenience-driven world undermines the very psychological resources we need for a fulfilling, long life. All content is for informational purposes only and is not medical advice.

The all-new WHOOP is here — now 7% smaller with 14+ days of battery life. New features like Healthspan show how your daily habits are affecting your rate of aging — and now you can check your blood pressure straight from your wrist. If you’re serious about performance, longevity, and actual progress — this is it. Sign up for a one-month free trial at WHOOP.com — or visit join.whoop.com/mentored for one month off your annual membership fee.
Eight Sleep’s newest generation, Pod 5. isn’t just another bed-frame add-on; it’s a high-tech mattress cover that actively adjusts to your body temperature throughout the night, cooling, warming, and even elevating your body when needed, all based on real-time data. The new Pod 5 introduces for the first time, a hydro-powered blanket system, utilising the same technology as the cover to extend temperature regulation across your entire body, not just the mattress surface. Clinically proven to increase quality sleep by up to one hour each night, it’s basically like having an AI-powered sleep coach, personal thermostat, and advanced health tracker working for you while you rest.
Head on over to eightsleep.com/project100 and use the code PROJECT100 (that’s Project one-zero-zero) and get up to $550 off your very own Pod 5. Trust me, your body will thank you for this investment in better sleep.
See omnystudio.com/listener for privacy information.