Project 100 with Mark Bouris

Most people taking supplements are wasting their money — not because supplements don't work, but because what they're swallowing never actually reaches the cells that need it. Bioavailability scientist George Kokkinis has spent 30 years at the intersection of chemistry, regulation, and human performance, and what he shares in this episode will change how you read every supplement label. From vitamin D3 and NMN to berberine, CoQ10, and omega-3s, we break down what's actually getting absorbed, what's heading straight to the toilet, and what to look for before you spend another dollar. This is the supplement conversation nobody in the industry wants you to have.
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In this episode of Project 100, I sit down with one of Australia's leading cardiothoracic surgeons to understand what's actually happening inside your heart, what your cholesterol numbers really mean, and why the gap between men and women in heart disease outcomes is more serious than most people realise. This is the conversation that will change how you think about what you're doing to your body right now — not in 30 years' time.
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Dr Stacy Sims is one of the world's leading exercise physiologists and nutrition scientists specialising in women's health, and she joins Project 100 to explain why the science women have been given is largely based on male data — and what that means for how women should actually train, eat, and protect their healthspan.
From the cellular differences between the sexes, to perimenopause, creatine, protein timing, Alzheimer's risk, and why sleep beats everything else — this is a conversation every woman (and the people who love them) needs to hear.
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Sebastian Oreb, better known as the Australian Strength Coach, has trained some of the world’s strongest athletes, including Hafþór Björnsson, Alex Simon, and elite professional athletes across multiple sports.
In this episode of Project 100, Sebastian breaks down the science of building muscle, explaining progressive overload, the best rep ranges for muscle growth, and why strength is one of the biggest predictors of healthy ageing.
We also cover:
Progressive overload explained simply
Compound vs isolation exercises
The best rep ranges for building muscle
How often you should train
Strength vs hypertrophy
Why muscle matters for longevity
Common gym mistakes that limit results
How to build muscle safely at any age
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Tim Piatowski is one of Australia's leading researchers on peptides and enhancement drugs, running the world's first steroid-checking trial and service.
In this conversation, we cover everything from what peptides actually are to the underground markets driving their use across Australia. Tim explains the science behind popular compounds like BPC-157 and GHK-Cu, the risks of unregulated products, and why Australia's regulatory approach is pushing people toward dangerous illicit markets. We also explore the potential for peptides in healthy ageing, injury recovery, and why our government's silence on this growing trend is creating more problems than solutions.
We speak about:
• What peptides are and how they work as signalling molecules
• BPC-157 for tissue healing and inflammation reduction
• GHK-Cu copper peptides for collagen synthesis and skin health
• Growth hormone releasing peptides like CJC-1295 and tesamorelin
• The contamination crisis in illicit enhancement drugs
• Legal pathways vs underground markets in Australia
• How peptides could transform healthy ageing and falls prevention
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