How do you treat alcohol use disorder (formerly called alcoholism) without requiring total abstinence? This week, Dr. Paul Kolodzik returns to The AGEIST Podcast to discuss his pioneering work around GLP-1s: using these medications to help people reduce their alcohol intake. Drawing on his background in emergency and addiction medicine, Dr. Kolodzik outlines how these off-label uses can drastically reduce consumption, often by 60–70%, even in heavy drinkers. Learn why harm reduction, not abstinence, is a realistic and medically valid path for many and how medication paired with behavior change is reshaping addiction treatment today.How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!Special Thanks to Our SponsorsOur Place: The top cookware brand for non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com. fatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.Maui Nui: The cleanest, most nutrient-dense red meat out there–high in protein, rich in antioxidants, and ethically harvested. Their new, subscription-only Ohana Reserve Aged Cuts are aged for 14 days to make for unforgettable flavor, plus their to-go venison sticks are perfect for healthy snacking. Right now, Maui Nui is offering a free 12-pack of their jerky sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.Key Moments“The better way to go for many people is to be completely abstinent. But I don’t think it’s the only way to go.”“Almost universally, people that are put on GLP-1s decrease their drinking.”“Alcohol withdrawal kills people... opiate withdrawal feels terrible, but it doesn’t kill people.”Connect with Dr. KolodzikWebsite (The Metabolic MD)North Dayton Addiction & Recovery ServicesConnect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!
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1:00:02
Brian MacKenzie on Breath, Stress, and Resilience
Brian MacKenzie has trained some of the world’s top athletes, but today his focus is on something far more universal: how we breathe and regulate stress. In this episode of The AGEIST Podcast, he breaks down why breath control is the most underutilized tool for improving health, sleep, and performance at any age. He explains how the nervous system can be trained just like a muscle, offering practical tools to build resilience and adaptability in daily life. Tune in to walk away with new strategies for reducing stress, sleeping better, and aging stronger through intentional breathing and recovery practices.Special Thanks To Our SponsorsTimeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.Our Place: The top cookware brand for non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com. 3 Key Quotes“The nervous system is trainable, and most people don’t even realize they can influence it.”“If you can’t breathe well, you can’t move well, and you certainly can’t recover well.”“Stress isn’t the problem—our inability to regulate it is.”Connect with Brian MacKenzieWebsiteInstagram (@brianmackenzie)Books: Unplugged: Evolve from Technology to Upgrade Your Fitness, Performance & Consciousness and Power Speed EnduranceTune in to hear more from Brian MacKenzie on this episode of The AGEIST Podcast or check out the full interview transcript.Say hi to the AGEIST team!
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1:17:12
Katy Bowman Says Stop Over-Exercising
What if the aches and pains of aging weren’t inevitable but simply a sign of movement malnourishment? Katy Bowman, biomechanist and author of several books, including Move Your DNA, returns to challenge everything you thought you knew about exercise and health. She introduces the idea of a “movement diet”—a diverse mix of postures and motions your body needs daily for optimal function—and breaks down how to rethink movement beyond the gym. Plus, she explains why sitting on the floor could be more beneficial than a workout and how every activity in your day, from chores to rest, can become an opportunity to move better.How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!Special Thanks to Our SponsorsBerkeley Life: Boost your energy, support heart health, and improve circulation with Berkeley Life Nitric Oxide. Use code AGEIST at berkeleylife.com for 20% off your first purchase—plus 10 free test strips to track your progress.LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.Maui Nui: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. Their venison sticks are perfect for healthy snacking on the go and their cuts of meat make for delicious, healthy meals. Right now, Maui Nui is offering a free 12-pack of their jerky sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.Key Moments“That ship [of movement] is leaving 10,000 times a day. Just get on that ferry.”“Your favorite mode of exercise, unfortunately, doesn't really make a well-balanced movement diet.”“You're much more malleable than you probably believe right now.”Connect with Katy BowmanWebsite (Nutritious Movement)Instagram (@nutritiousmovement)Books: Move Your DNA, Dynamic Aging, Say hi to the AGEIST team!
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1:00:16
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1:00:16
Dr. William Li on Reversing Vascular Damage
Can you heal your cardiovascular system with food? Dr. William Li returns to explain how inflammation, oxidative stress, and poor lifestyle habits damage your blood vessels–and what you can do to reverse it. From fruit peels to dark chocolate, he outlines specific nutrients that signal stem cells to “re-pave” your vascular highways. You’ll also learn the simple daily practices he recommends to keep your brain sharp, heart strong, and energy high well into your later decades.How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!Special Thanks to Our SponsorsTimeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.fatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.Key Moments“If your blood vessels are not healthy, you don’t stand a chance of actually living a long time.”“We can Zamboni our own blood vessels to get back to health if they’ve been damaged.”“The darker the chocolate, the more cacao… and the higher the levels of the polyphenol that calls out stem cells.”Connect with Dr. LiWebsite: drwilliamli.comCourse: Elevate Your MetabolismBooksConnect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!
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1:11:01
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1:11:01
Karen Salmansohn: Your To-Die-For Life
Best-selling author and behavior change expert Karen Salmansohn shares how mortality awareness can be one of the most powerful motivators for living with purpose. She explains her concept of a “near-life experience,” when people go through the motions instead of fully engaging in their lives, and how to break free from it. Karen offers practical tools—like writing your aspirational eulogy and linking core values to habits—that help listeners live with urgency and authenticity. Her upcoming book, Your To-Die-For Life, blends humor, science, and philosophy to guide readers toward more meaningful, regret-free living.How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!Special Thanks to Our Sponsorsfatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.Key Moments“Instead of being afraid of taking a risk, you get afraid of dying with the music still inside you.”“Identity is destiny. Who you think you are affects what you do.”“Numbers make things more alarming and thereby create the urgency that creates action.”Connect with Karen SalmansohnWebsiteBook: Your To-Die-For LifeInstagram (@notsalmon)Connect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!
The AGEIST podcast is where we rewrite life after 50. Hosted by David Stewart, founder of AGEIST and Super Age, we talk with extraordinary people—scientists, creatives, and thinkers—about living vibrantly in your 50s, 60s, 70s and beyond. From longevity science to emotional well-being, fitness to purpose, we explore the tools and mindsets that help us stay curious, energized, and deeply engaged with life. This isn’t about aging gracefully—it’s about living boldly.
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