In this episode, we explore the OCCUPI trial, a large randomized study comparing optical coherence tomography (OCT)-guided PCI to traditional angiography guidance in patients with complex coronary lesions. With over 1,600 patients enrolled, the trial showed that OCT guidance significantly reduced the rate of cardiac death, myocardial infarction, stent thrombosis, and target-vessel revascularization at one year. We discuss the trial design, key outcomes, and how these findings could shape the future of intravascular imaging in high-risk PCI cases.
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14:56
CALIPSO Trial: OCT-Guided PCI in Calcified Coronary Lesions
In this episode, we delve into the CALIPSO (Calcified Lesion Intervention Planning Steered by OCT) trial, a pivotal study evaluating the efficacy of optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) compared to traditional angiography-guided PCI in patients with moderate to severe calcified coronary lesions. Conducted across 12 centers in France, the trial demonstrated that OCT-guided PCI, utilizing a predefined lesion preparation algorithm, resulted in significantly larger minimal stent areas and improved stent expansion without increasing procedural risks. We explore the trial's design, key findings, and discuss the potential implications for interventional cardiology practice.
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16:42
RENOVATE-COMPLEX-PCI: Enhancing Outcomes with Intravascular Imaging
In this episode, we delve into the RENOVATE-COMPLEX-PCI trial, a pivotal study evaluating the efficacy of intravascular imaging-guided percutaneous coronary intervention (PCI) compared to traditional angiography-guided PCI in patients with complex coronary artery disease. The trial demonstrated that using intravascular imaging techniques, such as intravascular ultrasound (IVUS) or optical coherence tomography (OCT), led to a significant reduction in target vessel failure rates. We explore the study's design, key findings, and discuss how these results are influencing current interventional cardiology practices.
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18:54
Decoding Calcium: The OCT-Based Scoring Algorithm for PCI Planning
In this episode, we explore the OCT-based calcium scoring system — a powerful tool for assessing coronary calcium severity prior to PCI. We break down how this algorithm evaluates calcium thickness, arc, and length to guide lesion preparation strategies, improve stent expansion, and ultimately enhance patient outcomes. Tune in for a practical discussion on how this imaging-based approach is reshaping decision-making in the cath lab.
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6:01
ILUMIEN IV: Evaluating OCT-Guided PCI in Complex Coronary Lesions
In this episode, we delve into the ILUMIEN IV trial, a significant study comparing optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) with traditional angiography-guided PCI in patients with complex coronary artery disease, including those with diabetes. While OCT guidance led to a larger minimum stent area and a notable reduction in stent thrombosis rates, it did not significantly decrease the two-year rate of target vessel failure compared to angiography guidance. Join us as we explore the trial's design, key findings, and its implications for interventional cardiology practice.
Heart of the Data is your essential guide to the clinical science shaping the future of coronary care. This podcast dives deep into the latest studies, landmark trials, and evolving guidelines in interventional cardiology. Whether you're a clinician, researcher, or industry professional, each episode offers clear, insightful analysis of the data that matters—translating complex findings into real-world impact. From stents and imaging to physiology and pharmacology, Heart of the Data gets to the core of coronary innovation.
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