The Dr. Gabrielle Lyon Show

• Neuroscientist Explains MDMA and The Science of Social Connection | Dr. Ben Rein Ph.D.

  Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this fascinating episode, Dr. Gabrielle Lyon talks with neuroscientist Dr. Ben Rein, PhD (author of Why Brains Need Friends), about the science of social connection, emotion, and cognitive health. Dr. Rein, an expert in neurobiology and psychedelic research, reveals the cutting-edge studies that explain why loneliness is as damaging as smoking and how our digital world is affecting our brain's ability to connect.They discuss the neurochemistry of love, the controversial use of MDMA in therapy, and whether AI can ever truly replace human intimacy. This conversation provides an essential look at the biological drivers of happiness, performance, and long-term brain health.Chapter Markers:0:00 - MDMA (Molly): The History & Therapeutic Benefits 5:59 - The Legal Status of MDMA for PTSD 6:44 - The Safety and Effectiveness of MDMA in Clinical Trials 8:29 - PTSD (The Amygdala Alarm) 9:41 - How MDMA Soothes the Amygdala to Access Memory 11:42 - Is There an Alternative to MDMA? (Ketamine's Mechanism) 13:16 - Ketamine and Neuroplasticity for Depression 15:48 - Botox and Empathy: 18:12 - The Problem of Volume: How Screens Depersonalize Interaction 19:48 - The Virtual Disengagement Hypothesis Explained 25:00 - Defining Cognitive and Emotional Empathy 29:43 - MDMA's Link to Serotonin & Social Reward 31:04 - Do SSRIs Have Pro-Social Effects? 36:10 - The Science of Likability and "Easy to Read" Faces 40:10 - Top 3 Ways to Be More Likable49:49 - The Likability Gap: Why You Underestimate How Well-Liked You Are 56:59 - The Neurobiology of Oxytocin, Dopamine, and Serotonin1:09:23 - The Goldilocks Zone of Empathy 1:15:58 - Narcolepsy 1:18:16 - Alcohol: Why the Neurotoxin is Bad for Brain Health 1:21:47 - Exercise and Neurogenesis1:22:27 - Sex, Orgasm, and Oxytocin Release 1:25:06 - Oxytocin During Childbirth Who is Ben Rein:Dr. Ben Rein is an award-winning neuroscientist and Chief Science Officer of the Mind Science Foundation, where he supports early-career researchers in neuroscience. He earned his PhD from SUNY Buffalo and completed postdoctoral training at Stanford University, publishing over 20 peer-reviewed papers on autism, empathy, MDMA, and digital behavior. Recognized by the NIH, the Society for Neuroscience, and Sigma Xi, he also serves as a scientific advisor to more than 20 organizations. With over one million followers and 75 million video views, Dr. Rein is celebrated for making neuroscience accessible to the public and has been featured by outlets such as Good Morning America, ABC News, and PopularMechanics.Thank you to our sponsors:BodyHealth: Use code LYON20 to get 20% off your first order https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/BON CHARGE Holiday Sale https://boncharge.com for 25% off Pique 20% off for life: https://Piquelife.com/DRLYONFind Ben Rein at: Website: https://www.benrein.com/Instagram: https://www.instagram.com/dr.benrein/#TikTok: https://www.tiktok.com/@dr.benrein?lang=enFacebook:

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• Sex Therapist explains The Science-Backed Guide to a Better Sex Life | Marianne Brandon

  Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this explosive episode, Dr. Gabrielle Lyon sits down with relationship expert Marianne Brandon to confront the modern crisis of intimacy and sexual wellness. They dive into how the digital world—including porn, AI companions, and VR technology—is creating an evolutionary mismatch that clashes with our primal needs for bonding, leading to rising loneliness and sexual dysfunction.Dr. Lyon and Marianne Brandon explore the science behind what truly impacts performance, from erectile dysfunction (ED) and hormonal imbalances to the neurological effects of stress. This is a must-watch for couples, parents, and anyone navigating romance in the digital age.----------Chapter Markers0:00 - Intro0:49 - The Primal Need for Sex vs. The Digital World1:10 - The Hidden Cause of Erectile Dysfunction (ED)2:10 - The Loneliness Crisis: Gen Z, AI, and Intimacy3:50 - Do Women and Men Experience Desire Differently?5:15 - Stress is the #1 Libido Killer6:30 - Porn and AI: Is Sexting with a Bot Cheating?8:05 - The Surprising Impact of VR Porn on Sperm Quality9:30 - Action Plan: The #1 Move to Improve Your Sex Life TodayWho is Marianne Brandon:Dr. Marianne Brandon is a licensed clinical psychologist and a diplomate in sex therapy, recognized for her expertise in technologies impact on intimacy, evolutionary influences on human sexuality, and cultivating a more exciting sexual connection in long-term relationships. Dr. Brandon is best known for her forward-thinking work on the future of intimacy through blogging, lecturing, and podcasting. Her popular Psychology Today blog, “The Future of Intimacy,” explores emerging trends in technology and human connection. As a continuing education provider, she lectures on sex tech’s impact on intimacy as well as the impact of technology on humanity. Together with her husband, urologist Dr. Abraham Morgentaler, she co-hosts the podcast “The Sex Doctors,” bringing expert insight and candid dialogue to listeners on all aspects of sex, relationships, and technology’s transformative role in our lives. Drawing from nearly three decades of clinical experience, she offers psychotherapy focused on relationship issues and sexual concerns, with a reputation for blending clinical skill and compassionate care.This episode is brought to you by: BodyHealth - Get 20% off your first order with code LYON20 - https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/Timeline - Get 20% off your order - https://timeline.com/LYON OneSkin - Get 15% off with the code DRLYON – https://www.oneskin.co Find Marianne Brandon at: Website: https://www.drbrandon.net/LinkedIn: https://www.linkedin.com/in/mariannebrandon-59224513X: https://x.com/drbrandonFind Dr. Gabrielle Lyon at: Instagram:@drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a...

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• The Menstrual Cycle DECODED: Fertility, PCOS, and the New Science of Hormones

  Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this episode, Dr. Gabrielle Lyon sits down with Dr. Heidi van den Brink; one of the only scientists in the world studying the ovarian transition from fertility to menopause. Together, they unpack what textbooks and wellness influencers often miss: the biology behind how your ovaries, uterus, metabolism, and nutrition interact across every stage of a woman’s life. Dr. Heidi reveals the never-before-seen dynamics of the ovarian cycle, how follicles develop in “waves,” and what really happens during the menopause transition. They discuss how undernutrition, obesity, and metabolic health shape reproductive hormones; why early menarche and delayed ovulation matter for long-term health; and the surprising connection between your gut microbiome, bile acids, and fertility. If you’ve ever been told to “balance your hormones” with seed cycling, apps, or supplements, this episode separates myths from mechanisms. It’s a masterclass in understanding the science of your hormones and how to truly support reproductive health through every decade of life.Chapter Markers0:00 - Can You Get Pregnant While on Your Period? 1:21 - Intro to Dr. Heidi & Ovarian Cycle Research 3:39 - The Uterine Cycle vs. The Ovarian Cycle 6:19 - Follicle Waves: The Hidden Drama in Your Ovaries 10:38 - Novel Discovery: Follicle Waves in the Luteal Phase 12:00 - Why One Follicle is Selected for Ovulation 13:17 - Does Nutrition Affect Ovarian Function? 14:48 - The Variation in Menstrual Cycles (It's Not Always 28 Days) 17:23 - The Impact of Obesity on the Ovarian Cycle 18:11 - The Problem of Luteal Phase Defects & Fertility 24:52 - Ovarian Morphology as a Bio-Marker of Health 26:54 - How Undernutrition Affects Ovarian Health 31:56 - The Metabolic Tipping Point of PCOS (Polycystic Ovary Syndrome) 33:26 - The Myth of the "String of Pearls" Ovary 35:25 - The Menopause Transition & Rogue Follicles 39:04 - Can We Predict Menopause by Scanning Ovaries? 45:59 - Early Menarche (First Period) and Long-Term Disease Risk 48:33 - The Surprising Link Between Puberty Timing and Environment 52:28 - The Role of Leptin in Reproductive Health 55:50 - Debunking the Myth: Can Nutrition Cure PCOS? 59:07 - PCOS Diet Myths (Fruit, Timing, and Supplements) 1:04:40 - Fish Oil for Menstrual Cramps (Dysmenorrhea) 1:08:37 - Breakthrough: Bile Acid, The Gut Microbiome, and Ovulation 1:11:50 - Closing RemarksWho is Heidi Vanden Brink:Dr. Vanden Brink is a reproductive physiologist with over a decade of research in nutrition, metabolism, and female reproductive health. Her work focuses on how diet and metabolic conditions like obesity influence reproductive development during adolescence, with the goal of preventing disorders such as PCOS.Find Heidi Vanden Brink at: Texas A&M University: https://nutrition.tamu.edu/people/vanden-brink-heidi/ Google Scholar:

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• TRT Risks & Rewards: Your Testosterone Replacement Therapy Questions Answered

  In this highly requested AMA, Dr. Gabrielle Lyon addresses the most critical questions surrounding male hormone health. Dr. Lyon tackles the fear, stigma, and misinformation surrounding Testosterone Replacement Therapy (TRT), revealing why a low testosterone level is a major predictor of serious health issues like heart disease, bone fracture, and obesity.She breaks down the current medical consensus on TRT, the risks of replacement, the truth about dosing, and what every man over 40 needs to know about their hormone health. This is a must-watch to separate the bodybuilding myths from the medical facts.Chapter Markers0:00 - Intro: Low Testosterone is a Predictor of Heart Disease1:12 - The Penile Shrinking Myth: What Caused the Viral Frenzy2:20 - Testosterone Levels: The Truth About Aging in Men3:44 - The First Step: What Labs to Ask Your Doctor for4:22 - Why Men Need to Check Their Estrogen (Estradiol)6:13 - The Medical Cutoff for Low T and Androgen Sensitivity7:27 - Low T is Linked to Fatigue, Depression, and Fat Deposition9:27 - TRT and Cardiovascular Health: Is it Protective or a Risk?10:36 - Erectile Dysfunction Predicts Heart Attack Within 3-5 Years12:30 - The Stigma: Why Doctors Don't Check Testosterone13:00 - TRT vs. Steroids: Defining the Line14:21 - Infertility and TRT: What You Must Know15:18 - Safety: What are the Risks of TRT for Men?16:33 - The Stigma: Why Doctors Don't Treat Low T17:15 - TRT and Obesity: Treat Concurrently or Wait?18:10 - Menopause vs. Andropause: Why Men Don't Have to Decline19:34 - Testosterone Boosters (Ashwagandha, Tongkat Ali)26:11 - Different Forms of Testosterone Administration28:09 - Intranasal Testosterone for Less Impact on Fertility30:38 - Managing Expectations: How Long Until You Feel Better?33:00 - TRT and Muscle Gain: The Highs and Lows of Dosing36:47 - The Win-Win: Low Risk, High Reward39:00 - Blood Flow & Erectile Function: Cialis and Exercise40:17 - Semen Quality as a Marker for Overall Male Health41:29 - Parenting and the Cost of Unhealthy Humans41:45 - How to Raise Testosterone Naturally (The Pillars)42:29 - Low-Dose Cialis for Cardiovascular Health (Preemptive Strategy)43:59 - Dr. Lyon's TRT Journey and Early Concerns46:00 - OutroKey Takeaways:Low Testosterone is a major health risk. Low T is linked to an increased risk of bone fracture, heart disease, obesity, and diabetes.TRT is often protective. Contrary to the long-standing myth, replacing low testosterone to a healthy range does not increase the risk of cardiac events. It is, in fact, protective against cardiovascular disease.Erectile Dysfunction (ED) is a canary in the coal mine. ED can predict a heart attack within 3 to 5 years.Men can maintain high T levels. Testosterone levels in a healthy 75-year-old can be just as good as in a man in his 20s.The solution is often concurrent. For an obese or overweight man with low T, concurrent treatment with TRT and a lifestyle intervention is often the most responsible approach to provide the motivation needed for weight loss.Low-dose daily Cialis (2.5mg to 5mg) may be a viable preemptive strategy for cardiovascular health due to its blood flow benefits.This episode is brought to you by:Manukora - Get $25 off your Starter Kit at https://manukora.com/DRLYON Our Place - Use Code DRLYON for...

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• The Cancer Scare That Taught Jeremy Miner What Really Matters

  In this powerful episode, Dr. Gabrielle Lyon sits down with legendary sales expert and entrepreneur Jeremy Miner to discuss the foundation of success. Jeremy, the founder of Seventh Level, reveals the mental frameworks, communication skills, and commitment required to achieve peak performance in any area of life.Drawing from his own harrowing health scare and decades of experience coaching top performers, Jeremy shares candid insights into what separates the top 1% from everyone else. This conversation is not just about sales—it’s about the psychology of human connection, overcoming fear, and unlocking your full potential to build a more resilient and successful life.Who is Jeremy Miner:Jeremy Miner is an internationally recognized sales trainer and entrepreneur, best known as the founder of the sales training company 7th Level. He is the creator of the Neuro-Persuasion Sales Method and has a background in behavioral science, which he uses to train sales professionals. Previously, he was a highly successful, commission-only salesperson who was ranked among the top earners globally before retiring to start his training company. Timestamps: 0:00 - Intro3:06 - The Psychology of Success10:31 - How Fear Can Drive You14:40 - Communication Skills33:14 - The Power of Problem-Finding39:33 - The 4 Categories of Performance1:00:21 - Jeremy’s Cancer Scare1:12:32 - Advice for Mental ToughnessThis episode is brought to you by:Puori - Use code DRLYON for 20% off - https://puori.com/DRLYONCozy Earth - Use code DRLYON for up to 20% off - cozyearth.com/DRLYONBON CHARGE - Use code DRLYON to get 15% off your entire order - https://boncharge.com/DRLYONOneSkin - Get 15% off with the code DRLYON – https://www.oneskin.coFind Jeremy Miner at: Tiktok: https://www.tiktok.com/@jeremy_miner)Instagram: https://www.instagram.com/jeremyleeminer/)Facebook: https://www.facebook.com/JeremyLeeMiner/Offers: 7q.ai (http://7q.ai/) Waitlist: https://7q.ai/waitlistThe NEPQ PRIMER Community:

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