Peptide of The Week

Medical Disclaimer: We are not doctors. This content is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas are joined by Dr. Sam Borghei 20-year ER physician and owner of My Hair MD and Todd Padberg, General Manager of My Hair MD. We dig into hair restoration, natural-looking results, peptides for recovery, and the future of medicine.

Chapters:
00:00 – Intro & Guest Introduction03:18 – ER Life, Stress & Burnout06:14 – Personality Traits of ER Doctors10:08 – Transition Out of ER12:16 – Hair Transplant Process Explained18:04 – Procedure, Recovery & Limitations23:02 – Industry Trends & Patient Demand25:55 – Recovery, Peptides & Healing29:41 – Cost Breakdown & Expectations34:23 – Preventative Medicine & Telehealth Vision38:57 – Trust in Medicine Post-COVID43:12 – Peptides, Research & Future Outlook49:00 – Fitness, Hormones & Lifestyle54:54 – Contact Info & Outro

We cover:
🧬 Who is Sam Borghei? 20+ years in frontline ER medicine. Now owner of My Hair MD in San Diego and building a telehealth longevity platform focused on hormone optimization, weight loss, and personalized wellness.

✂️ How a hair transplant works FUE method: follicles are individually extracted from the DHT-resistant donor zone (back of the head). A 3,000–3,500 graft procedure involves 10,500+ steps over 6–8 hours. Grafts are sorted by size heavy grafts go to the back, singles go up front for a natural hairline. Those donor follicles do NOT grow back you have a finite supply (6,000–10,000 max).

🎨 The art of a natural result Hairlines are drawn jagged on purpose. Single hairs line the very front, temples are always filled in, and age-appropriate design matters. Artistry makes all the difference.

💉 Peptides & hair recovery Will used BPC-157, TB-500, and GHK-Cu shampoo post-transplant. BPC-157 and TB-500 support angiogenesis and blood flow to follicles. GHK-Cu supports collagen production and scalp stabilization. Will's results were fast with minimal shedding. PRP and laser light therapy are also available at My Hair MD.

💊 Medications that protect your transplant Dutasteride blocks DHT (which miniaturizes and kills follicles). Minoxidil increases blood flow to support graft survival. Both are commonly used alongside transplants.

💡 Pricing FUE: ~$3.50/graft | FUT strip: ~$3.00/graft. All-inclusive, no hidden fees, financing available. Online consultations offered. Contact Todd: [email protected]

🩺 Where medicine is heading Dr. Borghei's telehealth platform (Summer) offers personalized longevity plans biomarker monitoring, hormone optimization, weight loss, and hair restoration. His take: medicine is not one-size-fits-all, and the patient-physician relationship needs to come back.

🧠 Real talk on peptides Peptides are chains of amino acids with a remarkably low risk profile compared to many pharmaceuticals. FDA classifications are shifting, research is coming, and early adopters are already seeing results.

Follow for more:
My Hair MD: myhairmd.com | [email protected] 
JD's IG: @jd_denham_fit | 
Will's IG: @williamthaas | 
Community: skool.com/peptideresearchinstitute

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas sit down with returning guest Paul Bakhtiar president of telehealth for one of the largest peptide manufacturers in the country and keynote speaker at major peptide conferences for a deep dive into the entire growth hormone peptide category, IGF-1 LR3 protocols, how to stack without overlapping pathways, male fertility, and much more.

Chapters:
00:00 – Intro to Peptides & Telehealth
06:01 – Growth Hormone Overview
11:50 – Timing & Dosing Peptides
18:04 – AOD 9604 & Fat Loss
25:55 – Optimizing GH & Bloodwork
30:23 – GH Peptides Breakdown (Tesa, CJC, Sermorelin)
35:40 – Peptide Blends & Side Effects
44:29 – HGH Risks, Legality & Hormones
51:21 – Slu-PP-332 & Fat Loss
54:11 – Fasting, Cancer & Healing (BPC-157)
1:01:41 – NAD+, Protocols & Final Takeaways

We cover:
• Mixing Multiple Peptides in One Syringe: Why it's safe, how to do it right, and why you don't need to be a pin cushion
• The Full GH Peptide Hierarchy Explained: HGH vs. secretagogues vs. IGF-1 LR3 — what replaces, stimulates, and bypasses your natural growth hormone and when to use each
• IGF-1 LR3 Timing, Dosing & Cycle Length: Pre- vs. post-workout debate, why 20–40 mcg is the sweet spot, and why four to six weeks on with equal time off is the smart approach
• Tesamorelin vs. Sermorelin vs. CJC-1295: Strength rankings, dosing protocols, pituitary vs. blood plasma signaling, and why Tessa is Paul's top pick
• Ipamorelin Ratios for Women: Why equal blends can cause water retention and the case for keeping Ipa lower relative to Tessa or CJC
• IGF-1 Sweet Spot on Blood Work: Why 250–350 is the optimal range for fat loss, lean muscle, sleep quality, and cognitive function
• AOD-9604 & SLU-PP-332 Fat Loss Protocols: Proper AOD dosing, fasted cardio timing, and what the latest sloop studies show at higher milligram doses
• SS-31 Then MOTS-C for Mitochondrial Health: How to sequence them, the loading and maintenance phase for metabolic damage, and managing histamine reactions
• NAD+ Dosing Done Right — and What Happens When You Overdo It: Why 200mg per week is the sweet spot and what happens when you accidentally take 500mg
• Optimal Blood Work Markers for Testosterone: Total, free, DHEA, and SHBG targets for men and women — and why DHEA is a $25 fix most people overlook
• Male Fertility Protocol: HCG dosing, HMG every other day, N-clomiphene citrate, and why Paul avoids standard clomid
• BPC-157, Angiogenesis & Cancer Research: What the latest rat model studies show about wound healing vs. chaotic angiogenesis and why the risk conversation is shifting

📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.

You're a warrior. Act like one.

Follow Paul Bakhtiar:
Instagram: https://www.instagram.com/paulbakhtiar/
His Links: https://thepeptidepro.co/linktree

Follow us on social media:
JD's Instagram: https://www.instagram.com/jd_denham_fit
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! JD Denham and William T. Haas break down two powerhouse compounds NAD+ and Tesofensine covering what they are, how they work, real-world experience, and how to dose them right.

Chapters:
00:00 – Intro & Life Updates
05:30 – Parenting, Discipline & Boys
10:00 – Family, Values & Growth
18:30 – NAD Explained (What It Does)
25:30 – NAD Benefits & Real Results
29:00 – NAD Dosing & Side Effects
37:45 – NAD Cycles & Best Use
38:15 – Tesofensine Breakdown
42:00 – Energy, Focus & Fat Loss Effects
48:30 – Who Should (and Shouldn’t) Use It
52:30 – Dosing, Side Effects & Warnings
55:30 – School Platform & What’s Next
57:45 – Outro

🧬 What is NAD+? A coenzyme found in every cell in your body — essential for life. Powers over 500 enzymatic reactions and is critical for ATP (cellular energy) production. Declines dramatically with age: 100% at birth → 55% by age 40 → 34% by age 60. That decline is why we age — cells stop repairing and regenerating as well.

🔥 What NAD+ actually does – DNA and cellular repair — slows aging at the genetic level – Boosts natural cellular energy (not stimulant energy) – Neuroprotective — mental clarity, sharper focus, better brain function – Improves insulin sensitivity, lipid regulation, and cardiovascular function – Regulates inflammatory pathways and immune response

🧠 What is Tesofensine? A triple reuptake inhibitor (serotonin + dopamine + norepinephrine). Originally developed for Alzheimer's and Parkinson's — researchers noticed patients losing massive amounts of weight. Clinical trials showed 9–11% average body weight loss over 24 weeks.

⚖️ How Tesofensine works – Targets the brain — makes food stop giving you a dopamine hit – Reduces cravings for sweets and junk without fully suppressing hunger like GLP-1s – Does NOT spike blood sugar during fasting – Real energy increase — dopamine-driven motivation, not jittery stimulant energy – Great GLP-1 transition compound for weaning off without falling off track

💡 Real-world experience JD's first run felt off and tired — gave it a bad rep initially. Second run (last 3 weeks): loves the focused, clean energy, similar to Modafinil. Will: no more naps, more motivated, doesn't want to miss the day. Both agree — take it in the first half of the day, it will keep you up.

⚠️ What to avoid – Do NOT combine with SSRIs, SNRIs, or NDRIs (Zoloft, Wellbutrin, etc.) – Reduce caffeine — unnecessary stimulant overload – Do NOT combine with Modafinil – Not recommended for uncontrolled hypertension, bipolar disorder, or severe anxiety – Monitor blood pressure and run regular bloodwork

📺 Subscribe for more no-fluff peptide education every week.
Follow us on social media:
JD's Instagram: https://www.instagram.com/jd_denham_fit
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideoftheweekcommunity/about

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas break down why peptide companies skip advanced testing, how to stack IGF-1 LR3 without overdoing growth pathways, HGH safety for women post-menopause, fixing dangerously low testosterone at 28, and when to pull back Retatrutide and start TRT.

Chapters:
00:00 – Intro & Podcast Catch-Up
11:13 – Peptide Testing & Quality Concerns
20:16 – IGF-1, HGH & Stack Overlap
29:20 – Women’s Hormones & Hysterectomy
32:15 – Menopause, Weight Gain & Peptides
44:16 – Peptide Storage & Shelf Life
49:44 – NAD+ Crystallization Explained
51:37 – Growth Hormones for Women (Age 44)
59:44 – Low Testosterone & Mental Health (Age 28)
1:05:48 – Building Muscle Without Steroids (Athlete Q&A)

We cover:
• Why Peptide Companies Don't Test for Endotoxins & Heavy Metals: The real cost breakdown, why cheap peptides come with trade-offs, and how quality standards are rising
• Kisspeptin on TRT — Why It Won't Work: How TRT shuts down the signal kisspeptin needs and why HCG is the smarter choice for testicular health on cycle
• IGF-1 LR3 Stacking Rules: Why combining HGH, secretagogues, and IGF-1 all at once is too much on the same pathway — and how to rotate smarter
• Peptide Shelf Life & Storage Explained: Bacteriostatic vs. sterile water, why HGH is especially sensitive, and the practical rule of thumb for reconstituted peptides
• What Causes NAD+ to Crystallize: Dilution ratios, the importance of amber vials, and how to troubleshoot this common issue
• Kisspeptin After Hysterectomy: Why it likely won't work without the ovaries and why direct hormone replacement is the better path forward
• HGH Safety for Post-Menopausal Women: Addressing 50 pounds of menopause weight gain, why 1 IU of HGH beats secretagogues at this stage, and peptides that target brain fog, mood, skin, and libido
• CJC vs. Tesamorelin for Women with Water Retention: Why switching to Tessa and adding AOD is the cleaner approach when CJC causes uncomfortable fluid retention
• Low Testosterone at 28 — Fix That First: Why 315 total and 15 free testosterone explains SSRIs, brain fog, depression, and low energy better than anything else
• Building Lean Muscle for a Rugby Athlete Without Steroids: Why SLU-PP-332, Cardarine, creatine, and smart fasting are the right tools at 26
• BPC-157 Subcutaneous vs. Local Injection for Back Injuries: Why abdominal sub-q still works systemically and how BPC + TB-500 rebuild connective tissue post-dislocation
• When to Start TRT & HGH Mid Weight Loss Journey: Why 51 with 35 pounds already lost is the perfect time — and how to wean Retatrutide down the right way

📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.

You're a warrior. Act like one.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jd_denham_fit
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideoftheweekcommunity/about

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas break down two of the most underrated fat-burning peptides out there — HGH Fragment 176-191 and AOD 9604 what makes them different, how to use them, and why they deserve a spot in your cutting stack.

Chapters:
00:00 – Intro & Marriage / Work Balance
10:30 – AOD 9604 vs HGH Frag Intro
14:29 – AOD Origins & Fat Loss Benefits
19:13 – Half-Life, Dosing & How It Works
24:11 – School Community & Membership Update
27:05 – Which Is Better: AOD or Frag?
29:00 – Why Real Experience Matters
29:54 – Company Growth & What’s Next
31:13 – Hair Transplant Guest Preview
31:58 – Doctors Finally Talking Peptides
32:32 – Final Thoughts & Outro

We cover:
🧬 What these peptides actually are
– Both are fragments of the full 191 amino acid HGH chain
– HGH Frag 176-191 = the natural amino acid sequence (176–191)
– AOD 9604 = lab-engineered version (177–191), modified for longer duration and better safety profile
– AOD received FDA GRAS (Generally Recognized As Safe) status in 2014
– Developed at Monash University in Australia 🇦🇺

🔥 What they do (and what they don't)
– Target lipolysis — fat burning, especially visceral/abdominal fat
– Boost metabolism and increase energy expenditure
– No IGF-1 spike
– No hypoglycemia risk
– No effect on growth — zero cancer concern
– 30–50% greater fat reduction vs controls in studies
– Obese participants lost significantly more body fat vs placebo over 12 weeks

⚖️ HGH Frag 176-191
– Natural fragment of the HGH chain
– Half-life: ~30 minutes
– Can dose 1–2x daily (some go 3x)
– Best taken fasted — morning or pre-workout
– Cycle length: 8–12 weeks
– Comes in 5mg bottles (they don't like water — keep it small)

👑 AOD 9604
– Lab-engineered, modified for longer stability
– Half-life: 30–60 minutes
– Daily dosing (can split AM/PM)
– Additional benefit: potential cartilage and joint repair (not seen with HGH Frag)
– Cycle length: 12–16 weeks
– FDA GRAS status — one of the safest peptides available
– JD's personal top 5 — shines brightest stacked with other cutting compounds

🚫 What NOT to combine
– High-dose corticosteroids
– Full-dose HGH (defeats the purpose of the targeted safety advantage)
– Insulin (just don't)

✅ What pairs great with these
– GLP-1 agonists (Semaglutide, Tirzepatide)
– 5-Amino-1MQ
– L-Carnitine
– BPC-157 + TB-500 (especially with AOD for joint/cartilage synergy)
– CJC + Ipamorelin (boosts metabolism and fat burning further)

🧠 Real-world take
– AOD shines brightest when stacked — it's a force multiplier for your cutting stack
– HGH Frag works fast and hits hard on a short half-life
– Both are tools — results depend on diet, training, and what you stack them with
– Individual response varies — don't let your gym bro's experience dictate yours

🔑 Bottom line: If you want pure fat burning with virtually zero downsides, these two are as clean as it gets.

🧪 This isn't theory this is real-world experience working with hundreds of people and seeing what actually works.

📺 Subscribe for more no-fluff peptide education every week.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jd_denham_fit
Will's Instagram: https://www.instagram.com/williamthaas/
Join Our Community: https://www.skool.com/peptideresearchinstitute/about