Peptide of The Week

We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas break down two of the most powerful peptides for completely different but equally life-changing purposes: Kisspeptin for fertility and hormonal signaling and Thymosin Alpha-1 for immune system dominance.

If you’re trying to have a baby, coming off a fertility struggle, constantly getting sick when you travel, or dealing with autoimmune and inflammation issues this is a must-listen.

Chapters:
00:09 Intro, Cold Weather Banter & Podcast Upgrades 
06:40 Kisspeptin Overview: How It Works for Fertility
10:45 Kisspeptin for Men vs Women (Hormones, Ovulation, Libido)
11:10 Why Kisspeptin Doesn’t Work on TRT
12:00 HCG vs Kisspeptin for Fertility on TRT
20:00 Kisspeptin Dosing, Frequency & Shutdown Risk
26:20 Thymosin Alpha-1: Immune System Master Peptide
30:10 Autoimmune Benefits, Inflammation & Cancer Support
31:00 TA-1 for Travel, Illness & Real-World Use
32:45 TA-1 Dosing Protocols & When to Run It
34:50 Sleep, Recovery & Why Most People Stay Sick
39:40 Botox, Snap-8 & TMJ Side Discussion
40:50 Future Podcast Plans, Guest Doctors & Outro

We cover:
👶 Kisspeptin The fertility signal peptide
– Activates the hypothalamus → GnRH → pituitary → LH & FSH cascade
– Drives natural testosterone production in men
– Stimulates sperm production and fertility
– In women: supports follicle development, ovulation, estrogen & progesterone
– Powerful tool for pre-pregnancy hormone optimization
⚠️ Does NOT work while on TRT (HPTA is suppressed)

💉 TRT fertility reality check
– Why exogenous testosterone shuts down the fertility signal
– HCG as the primary on-TRT fertility solution
– Real-world success using 1,000 IU 3x/week protocols
– HMG: the true LH + FSH option (but high cost)

🛡 Thymosin Alpha-1 The immune system commander
– Trains and multiplies T-helper & T-killer cells
– Enhances pathogen detection and destruction
– Immune modulation (not just stimulation)
– Reduces systemic inflammation
– Supports autoimmune balance
– Used globally for hepatitis, sepsis, cancer support & viral defense

✈️ Why TA-1 is the travel essential
– Massive reduction in getting sick from flights
– Rapid recovery when illness starts
– Ideal stacked with glutathione & B-12 for immune response

🔥 Inflammation & autoimmune applications
– Helps regulate overactive immune response
– Can improve chronic inflammatory conditions
– Individual response matters trial and feedback is key

💡 Whether your goal is having a child, restoring natural hormone signaling, staying healthy while traveling, or building a bulletproof immune system these two peptides attack the problem at the root.

🧪 This isn’t theory it’s real protocols, real outcomes, and real-world application.

📺 Subscribe for weekly no-fluff deep dives into the most powerful healing and performance compounds on the planet.

We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this week’s Peptide Q&A, JD Denham and William T. Haas break down real-world protocols for fat loss, brain performance, longevity, and how to build stacks that actually match your goals plus a deep dive into peptide safety and sourcing. No fluff. No scripts. Just straight talk from experience.

Chapters:
00:09 Intro, Rainy Day Banter & Q&A Format Explained 
03:10 Why Different Personalities Make the Podcast Work
08:30 Stalled Fat Loss on GLPs & When to Switch Compounds
17:20 Bodyweight Training, Muscle Loss & Metabolism
22:40 Reta Stacks for Fat Loss Without Losing Muscle
31:00 Fasting, Food Timing & Peptide Use
38:20 Vetting Peptide Companies, COAs & Pricing Reality
48:40 TRT, Libido Issues & Estrogen Troubleshooting
57:10 CJC-1295 With vs Without DAC (First-Time Use)
1:00:10 Best Fat Loss Stacks to Run With Reta
1:09:45 SS-31, Mitochondria & Cardiovascular Support
1:11:10 When Surgery Beats Peptides for Healing
1:12:15 Podcast Growth, Future Plans & Outro

We cover:
🧠 Semax & Selank Longevity: BDNF, neuroplasticity, cycling vs continuous use, performance timing, and anxiety dosing strategies
🏋️ Ex-Powerlifter Recomp Plan: TRT + RETA setup, AOD, SLU-PP-332, 5-Amino-1MQ, GH for muscle retention, and how to train heavy for fat loss
🔥 Training for Body Recomposition: Short rest periods, compound lifts, fasting integration, and hitting muscles twice per week for metabolic output
👩 Low-Dose RETA for Women: When to titrate up, why lowest effective dose matters, preserving muscle with Tesa-IPA, and where KPV fits
🍽️ RETA Reality Check: Appetite control vs starvation, habit change, food quality, and why it’s not a magic shot
🧬 Thyroid Cancer Warning Explained: Rodent data vs human risk, MEN2 history, quality-of-life decision making, and doctor conversations that matter
⚙️ What to Stack with RETA: Fat-loss stacks vs mitochondria, anti-aging protocols, NAD timing, and GH for 40+ optimization
📉 Long-Term Low-Dose RETA: Metabolic health benefits, desensitization myths, titrating down vs coming off, and maintenance strategy
🏃 Endurance Athletes & Fueling Issues: When RETA suppresses calories too much, MK-677/IPA for appetite, GH timing, and recovery support
📦 Peptide Safety & Contamination: China raws vs U.S. bottling, endotoxin testing, heavy metals, COAs, real cost of proper testing, and how to vet companies
🫀 Heart Health & SS-31: Mitochondrial integrity, energy utilization, and realistic expectations with structural conditions
🌍 Lifestyle Over Peptides: Why training, movement, diet, and daily activity are still the foundation everything else amplifies
🎙️ What’s Next for the Podcast: Possible guest episodes and expanding education for women’s hormones

💡 Peptides amplify the work they don’t replace it. Dial in training, nutrition, recovery, and lifestyle to unlock their real power.

📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.

You’re a warrior. Act like one.

Follow us on social media: 
JD's Instagram: https://www.instagram.com/jd_denham_fit
Will's Instagram: https://www.instagram.com/williamthaas/
Warrior-Makers page: https://www.instagram.com/warrior_makers_supplements/

We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Dr. Tyler from Action TRT to break down the real root of modern men’s health decline low testosterone and the foundational protocols that are changing lives: TRT, HCG, and Growth Hormone.

From why testosterone levels are crashing in younger men to the truth about estrogen, fertility, libido, and long-term optimization, this episode is a masterclass in building the hormonal base that everything else depends on.

Chapters:
00:09 Intro & Why Testosterone Is So Low Today 
02:40 How a Proper TRT Clinic Evaluates New Patients
06:15 Total vs Free vs Bioavailable Testosterone Explained
11:00 HCG: Fertility, Testicular Function & Mental Benefits
16:45 Enclomiphene vs HCG (What Actually Works Long Term)
22:30 TRT Dosing Mistakes & The AI/Estrogen Debate
30:05 Stop Chasing Numbers Treat Symptoms & Performance
35:45 Injection Methods, Frequency & Why Pellets Fall Short
42:00 Testosterone + Growth Hormone for Longevity
46:00 Top Peptides Right Now (Reta, Tesamorelin, BPC-157)
50:55 How to Start TRT the Right Way & Clinic Philosophy
53:20 Low Libido on TRT What’s Really Happening
54:40 Outro

We cover:
🧬 Why testosterone is at epidemic-level lows
– Environmental toxins, plastics, pesticides, food quality & lifestyle
– Why today’s 30-year-olds have the levels of older generations in decline
– The real symptoms that bring men into the clinic: fatigue, mood, fat gain, low drive

🧪 The lab work that actually matters
– Total vs Free vs Bioavailable testosterone explained in real terms
– Why most traditional clinics miss the full hormonal picture
– Thyroid, CMP, PSA, SHBG, estrogen & metabolic markers

💉 TRT done correctly vs cookie-cutter protocols
– Why one-size-fits-all dosing fails
– Injection frequency & why twice per week is the modern standard
– SubQ vs IM: absorption, stability, and real-world application
– Why pellets and creams often limit precision and adjustment

🔥 HCG – the “special sauce” of TRT
– Keeps natural production active & preserves fertility
– Prevents testicular shutdown
– Supports mental well-being & hormonal balance
– Why running TRT without it can create long-term issues
– Fertility protocols and real patient success stories

⚖️ Enclomiphene vs HCG – what actually works long term
– Why oral stimulation fails for many men
– Pituitary response variability
– Side effects: mood swings, headaches, crashing levels
– The difference between temporary lab improvements and real symptom resolution

❤️ Estrogen in men – the most misunderstood hormone
– 50% of libido & erectile function comes from estrogen
– Why crushing estrogen destroys performance & sex drive
– The difference between metabolic high estrogen vs TRT-optimized conversion
– Why symptom resolution matters more than chasing lab ratios

🚀 Growth Hormone the longevity multiplier
– Low-dose GH for recovery, fat loss, sleep & cellular repair
– Why it’s called the “fountain of youth” in clinical practice
– The synergy of optimized testosterone + GH
– Performance, energy, and long-term health benefits

📊 Optimization is individualized
– There is no universal “perfect number”
– The real metric: energy, performance, recovery, libido, sleep & body composition
– Small dose adjustments that create massive quality-of-life changes

🧪 This is real clinical experience, real patient outcomes, and real protocols not forum theory.

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this week’s Peptide Q&A, JD Denham and William T. Haas open up with gratitude, growth, and real talk about discipline then dive deep into hormone issues, peptide stacking, libido struggles, and practical injection strategies. No fluff. No scripts. Just experience.

Chapters:
00:09 Gratitude, Growth & How the Podcast Started 
09:44 Finasteride, DHT & Back Acne
17:14 Mixing Peptides, Reconstitution & Travel Storage
29:09 DSIP Dosing & Sleep Optimization
31:09 Glow Serum, Sloop Tabs & Naltrexone
38:19 Adipotide, Thymalin & Immune Peptides
42:29 Wolverine Stack: Dosing for Maintenance vs Injury
46:29 TRT Libido Issues & Hormone Troubleshooting
58:54 CJC/IPA, Fat Loss Stacks & Retatrutide
1:02:29 TRT for Older Men
1:03:39 GHK-Cu Topical vs Injectable + Water Retention in Women
1:07:54 Upcoming Guests & Outro

We cover:
🔥 Back Acne on TRT: Why estrogen not DHT  is usually the culprit, when (and when NOT) to use AIs, and the truth about finasteride vs dutasteride
💉 Estrogen Management: Injection frequency, SHBG, prolactin, and how poor AI timing can actually make things worse
🧠 Libido Loss on TRT: Why erections can be psychological AND hormonal, prolactin considerations, cabergoline, calming peptides, and performance anxiety
💊 Cialis Strategy: Why daily low-dose Cialis may work better than “as needed” dosing
🧬 Mixing Peptides in One Syringe: What’s safe, what’s ideal, needle dulling, scar tissue risks, and when to switch to fresh pins
🧊 Peptide Travel & Storage:** How long peptides can sit at room temp, when refrigeration matters, and what to look for in a reputable supplier
😴 DSIP Dosing: Sub-Q protocol, realistic expectations (it doesn’t knock you out), and how it enhances REM sleep
💆 Glow Serum vs Injectable GHK-Cu: Why topical formulations are different, post-laser healing benefits, and how often to apply
⚖️ Low-Dose Naltrexone: When it may help cravings or receptor sensitivity and why it’s not a magic fix for everyone
🧪 Thymalin & Adipotide: Why they’re less popular, safety concerns, and when thymosin alpha-1 is the better immune option
🚴 Wolverine Stack Dosing: Daily maintenance vs blast protocols for athletes rehabbing injuries and staying ahead of inflammation
🔥 RETA Stacking for Fat Loss: AOD, SLU-PP-332, 5-Amino-1MQ, and mitochondrial support for leaning out
👴 65-Year-Old Starting TRT: Why 197 total test at that age is a strong candidate for replacement and why quality of life matters
💧 Tesamorelin Water Retention in Women: Finding the sweet spot, dose adjustments, and why women often need much less
💋 GHK-Cu After Microneedling: Why purpose-built serums beat injectable peptides used topically

💡 Hormones are individual. Bloodwork matters. Injection frequency matters. Ego from doctors doesn’t help. Your body is a science experiment learn it.

📌 Subscribe for weekly no-fluff education, protocols, and real-world results.

You’re a warrior. Act like one.

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas break down one of the most misunderstood peptide categories out there: growth hormone secretagogues. From real GH to Tesamorelin to MK-677, this one is packed with nuance, strategy, and real-world results.

Chapters: 
00:00 Welcome Back & Super Bowl Banter
05:50 What This Episode Covers: Growth Hormone Secretagogues
06:45 GHRH vs GHRP Explained (Simple Breakdown)
12:50 Tesamorelin: Benefits, Fat Loss & Why It’s Top Tier
15:30 CJC-1295 (With vs Without DAC)
19:20 Age, Teens & Secretagogues (Who Should Not Use Them)
23:30 MK-677: Hunger, Muscle Gain & When It Makes Sense
26:50 Dosing Strategy, Timing & Cutting vs Bulking
29:00 Tesamorelin & Sleep Issues (How to Fix It)
34:30 Secretagogues vs Real HGH (What to Use & When)
38:20 Long-Term Benefits: Recovery, Aging & Fat Loss
41:20 TRT, Estrogen, AIs & What’s Coming Next
44:10 Outro & Final Thoughts

We cover:
🧬 GH Secretagogues 101: GHRH vs GHRP
– GHRH (Tesamorelin, CJC) tells the pituitary to make GH
– GHRP (Ipamorelin, MK-677, GHRP6) pushes the pulsing & release
– Why you need both sides of the equation for max effect
– Warehouse analogy explained: stock + shipping = full power

💉 Ranking the Peptides (Effectiveness vs Side Effects)
– Tesamorelin: 5/5 effectiveness, 2/5 side effects the king of fat loss & GH synergy
– Ipamorelin: Cleanest GHRP, low prolactin/cortisol risk
– CJC-1295 (no DAC): Powerful GH increase, occasional histamine response
– CJC w/ DAC: Long ester = higher blood levels but more estrogenic sides
– MK-677: Strongest hunger, fullness, and muscle but water retention & fatigue are real
– Hexarelin, GHRP6, GHRP2: Strong but outdated due to prolactin & side effects

📌 Side Effect Note:
– CJC rash/histamine reaction? Try KPV or Benadryl or switch to Tessa
– High prolactin? Avoid Hexarelin/GHRP6 or use Cabergoline as needed
– MK too strong? Dose at night to sleep through the hunger

🔬 Secretagogue Strategy & Dosing Tips
– Tesamorelin is FDA approved for reducing visceral fat not GH
– MK-677 best dosed based on goal:
– Bulking? Take AM to maximize food intake
– Cutting or appetite control? Take PM to sleep through hunger
– Pairing Tessa + MK = elite combo, but CJC might get suppressed by exogenous HGH

💡 Should Teens Use GH or Secretagogues?
– Hard no on peptides for performance in high school
– BPC/TB-500 for injuries? Yes.
– But MK-677 or secretagogues to bulk? Not needed teens are already full of GH
– “Let them eat more, train hard, and let nature do its thing.”

🧠 Bonus: Why Tesamorelin Might Affect Sleep
– Some users report restlessness due to GH-induced sympathetic activity
– Start low and titrate slowly (250mcg → 500mcg)
– Stay the course: sides usually subside as body adapts

🔥 HGH vs Secretagogues
– HGH = direct exogenous GH
– Secretagogues = stimulate your own GH pulses
– Take HGH in the morning (fasted) to avoid suppressing natural nighttime GH pulses
– Never take HGH at night if you still want your body to produce on its own
– Stack Tesamorelin + Ipamorelin at night = synergy
– HGH + Tesamorelin = powerful belly fat & aging stack
– HGH + CJC? Might suppress the CJC's value

📌 HGH Long-Term Benefits:
– Fat loss, sleep quality, muscle retention, faster recovery, skin tightening, and aging in reverse
– Plan: 1–2 IUs/day indefinitely
– JD & Will both planning to run growth long-term
– “This isn’t about youth. It’s about maximizing life.”

💬 Got questions or peptide topics you want broken down? Drop a comment below.

📺 Subscribe for more no-fluff, real science weekly.