Peptide of The Week

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover a teenage son with chronic boils, TRT for weight loss and low energy, MCT vs seed oil carriers, fasting on Retatrutide, fertility protocols for special forces veterans, and what to do when MOTS-C causes a lasting reaction.

Chapters:
 00:00 – Studio Updates & Upcoming Guests
09:15 – Gut Health, Immunity & Healing Protocols
14:09 – TRT, Weight Loss & Low Testosterone
20:03 – Women's Hormones, Energy & ADHD
26:01 – Fat Loss, Libido & TRT Optimization
32:00 – Injection Reactions & MOTS-c Side Effects
34:23 – Gut Inflammation, IBD & Healing Peptides
39:08 – Anxiety, Depression & Brain Peptides
41:36 – TRT, Carrier Oils & Performance
49:42 – Fasting, RETA & Muscle Retention
53:09 – Fertility, TRT & Family Planning

We cover:
• Teenage Son with Chronic Boils & Gut Issues: Why stopping antibiotics, running oral BPC and KPV, and getting a stool test done may matter more than any peptide
• TRT at 45 with 300 Pounds to Lose: Why waiting for weight loss to fix testosterone is swimming upstream and why starting low-dose TRT now changes everything faster
• ER Nurse with ADHD, Celiac & Low Energy: Why Modafinil beats Adderall long term, why Selank and Semax are the right pairing, and why hormones need to be checked first
• Low Energy & Low Libido on Retatrutide + TRT: Why rapid fat loss suppresses natural testosterone, why Kisspeptin doesn't work on TRT, and why HCG is the right call instead
• MOTS-C Allergy — What To Do: Why some people simply can't tolerate it, why SS-31 and NAD cover most of the same ground, and why Paul Bakhtiar has the same reaction
• IBD Protocol for Wife: Why oral and injectable BPC plus KPV are the right tools and how long you can realistically run them
• PSA Concerns on High-Dose TRT: Why DHT management matters, what estrogen symptoms to watch for, and when finasteride or dutasteride may be needed
• Coming Off Anti-Anxiety Meds: Why Selank, Semax, Tesofensine and PE2228 cover anxiety and depression from different angles and why meditation and movement still matter most
• Low Testosterone at 30 in Australia — MCT vs Seed Oil Carriers: Why MCT wins on purity and dispersal, why Proviron enhances TRT naturally, and what to watch for with post-injection pain
• Fasting on Retatrutide: Why Retatrutide actually protects muscle during fasting through insulin signaling and why training fasted accelerates results
• Special Forces Vet Trying for Baby #2: Why HCG, HMG and N-Clomiphene together beat Clomid alone and why TRT during conception is more doable than most doctors admit

📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.

You're a warrior. Act like one.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this episode of Peptide of the Week, JD Denham (live from Cabo) and William T. Haas break down Will's top 5 fat burners, JD's real-world stacks for a 47-year-old man needing to lose 70 pounds, a menopause protocol, and what a 21-year-old athlete should actually be taking.

We cover:
🔥 Will's Top 5 Fat Burners (in order)
– Retatrutide: triple agonist GLP-1, GIP, and glucagon. The undisputed #1. Kills food noise, keeps brain sharp while fasted, no hangry response. Nothing comes close
– Cagrilintide: the appetite suppressant add-on Reta is missing. Better and safer alternative to stacking tirzepatide with Reta - Novo Nordisk already made Cagrisema for a reason
– HGH: boosts metabolism, improves sleep, builds lean muscle, reduces fat. You notice it most when you stop. HGH Frag 176-191 and AOD are great honorable mentions for those already lean
– Tesamorelin: the only compound proven to spot-burn visceral fat. FDA approved. Dose at night fasted for best results do NOT take at the same time as Reta (insulin blunts it)
– MOTS-C: exercise mimetic on a cellular level. Thousands of people reporting great fat loss results. Boots energy, ATP, and keeps you moving more throughout the day
– Honorable mentions: SLUPP-332, 5-Amino-1MQ, Tesofensine, Clenbuterol, Cardarine GW501516, T3 thyroid, Liposa/MIC injection, L-Carnitine

💪 JD's Stack — 47-Year-Old Man, 70 Pounds to Lose, Desk Job
– Step 1: Get bloodwork - almost guaranteed to be hormonally deficient
– TRT: non-negotiable base. Sleep, clarity, energy, sex drive all improve within weeks
– HGH: sleep, recovery, anti-aging, lean muscle, fat burning - must for anyone over 40
– Retatrutide: holy grail for fat loss. Works exponentially better when hormonally optimized
– Wolverine Stack (BPC-157 + TB-500): he hasn't trained, his tendons need support — mandatory
– KPV: 47 years of bad eating has wrecked the gut. Fix the gut, fix everything
– Diet: 90-day carnivore, intermittent fasting Mon/Wed/Fri (eat 12–8PM), weight train 4 days/week, HIT training 3 days/week

🦋 Menopause Stack
– Cellular energy: NAD+, SS-31 (repair first), then MOTS-C
– Mood/brain fog: Semax + Selank together dopamine, serotonin, anxiety relief
– Intimacy/dryness: PT-141 goes from first gear to fifth fast
– Weight gain: Retatrutide even at low doses for women who don't need major weight loss
– Skin/hair/nails: KLOW (GHK-Cu + KPV + BPC-157) collagen, gut health, hair thinning, fine lines

🏊 21-Year-Old Competitive Athlete
– Keep it simple their body heals itself
– Creatine + high protein + eat more food
– Wolverine if they have an injury only peptide worth adding at this age
– SLUPP for stamina and nutrient partitioning if needed
– No testosterone, no secretagogues, no HGH their body produces plenty
– Cardarine would help massively but is WADA banned skip it if competing

📺 Subscribe for more no-fluff peptide education every week.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this week's Peptide Q&A, JD Denham (live from Cabo) and William T. Haas cover diet and exercise for women over 50, surviving on two to three hours of sleep, TRT pros and cons, mixing peptides in bulk vials, gut healing miracles, and how peptides are actually made.

Chapters
00:00 – Cabo Update & Will's Wedding Prep
03:52 – Weight Loss: Diet vs. Peptides
11:28 – Can You Survive on 2–3 Hours of Sleep?
15:20 – Mixing Multiple Peptides the Right Way
18:13 – Healing Chronic Gut Issues with Peptides
22:17 – HGH for Women Over 60
24:49 – Is TRT Worth It? Pros & Cons Explained
31:15 – Recovering Faster from Training & Injuries
35:03 – Productivity Guilt, Family & Finding Balance
41:08 – Brain Fog, Focus & Cognitive Peptides
45:08 – How Peptides Are Actually Made
52:37 – Upcoming Guests & What's Next

We cover:
• Diet & Exercise for Women Over 50: Why resistance training beats cardio every time, why protein is the non-negotiable, and how lifting weights raises metabolism for 24 hours after the workout
• Surviving on 2-3 Hours of Sleep: Why DSIP, SS-31, MOTS-C, TA-1 and NAD can help but won't save you long term and why Modafinil was literally made for shift work disorder
• Pre-Filling a Week's Worth of Peptides in One Vial: Why the math works perfectly for SS-31 and MOTS-C and which compounds should never be mixed with others
• Gut Healing Miracle on BPC & KPV: Why these two are the real healers inside Clow, why oral versions work well for gut-specific issues, and how long you can safely run them
• HGH at 65 for a Female on HRT: Why secretagogues likely won't cut it at this age, why 1 IU of exogenous HGH is the right call, and how to get access
• TRT at 43 with 560 Total Testosterone: Full breakdown of pros, cons, estrogen management, DHT and hair loss risk, and why free testosterone of 12 is the real problem
• Recovery Stack for a 41-Year-Old Muay Thai Athlete: Why a Tesamorelin/Ipa or CJC/Ipa blend is the top recovery addition and why TRT status changes the whole answer
• Productivity Guilt as a Sober Dad: Why blocking family time like a work appointment works, why rest is actually production, and why not drinking is the most important decision you're making
• ARA-290 for Neuropathic Pain: Why this peptide has promise for nerve pain and why JD and Will are testing it soon
• How Peptides Are Actually Made: Solid phase peptide synthesis explained simply, why raws all come from China, why BPC can never be patented, and what the FDA's clinical trial rules actually protect

You're a warrior. Act like one.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this episode of Peptide of the Week, JD Denham and William T. Haas sit down with Trevor Kruder the man they call the Godfather of Peptides. 12 years in the industry before most people knew what a peptide was, Trevor has built one of the most comprehensive peptide and hormone companies in the world. This one is packed.

Chapters
00:00 – Intro, Travel Plans & Life Updates
06:29 – Hormones vs. Peptides: Where to Start
13:30 – How Trevor Built a Peptide Empire
18:18 – Hiring Great People & Building Teams
22:23 – Is It Too Late to Start a Peptide Business?
31:36 – Leadership, Growth & Managing Success
37:28 – Social Media, Misinformation & Peptides
41:05 – Why China Dominates the Peptide Industry
46:22 – The Reality of Starting a Peptide Company Today
50:52 – Educating Doctors & Growing the Industry
53:08 – The Future of Peptides & Telehealth
57:20 – Final Thoughts & Closing Advice

We cover:
🏗️ How it all started
– Started synthesizing peptides from scratch 12 years ago with $30,000 and a small lab
– Spent 7 years building with almost no market nobody knew what peptides were
– Built a 20,000 doctor network and scaled to $170–180M in under 2 years
– Now operates 44+ companies including telehealth, pharmacies, drug manufacturing, research, cosmetics, hair restoration, and more
– 500–800 employees across multiple sites

🏥 What he's built
– Three telehealth companies and three 503A pharmacies
– 50-state hormone license supplies Walgreens, CVS, and rare disease medications to every major university in the US
– Two 503B sterile injectable facilities (two more being built)
– Research manufacturing sites running 12–14 IRBs and INDs per year
– AlphaSync described as Amazon for doctors, full platform for ordering peptides and hormones at a fraction of market cost
– New brick-and-mortar wellness center opening: IV, hyperbaric, red light, full gym, laser treatments all under a membership model

🔬 What's coming — peptides to watch
– FLGR-242 (Follistatin 242): modified follistatin that actually adds muscle one of the most exciting muscle builders emerging
– Lepto: GLP + GIP + Glucagon + IGF-1 once every two weeks injection, helps with weight loss while protecting muscle from wasting
– Albumin-bound semaglutide: 1/10th the normal dose with the same result no receptor burnout
– Oral peptide delivery system: coats peptide to survive digestion, bypasses liver, enters lymphatic system 24x more bioavailable in models. Human trials starting in 30 days

🌏 The peptide industry reality
– China makes 80% of the world's peptide raw materials and that's not changing their facilities cost $300M–$1B+
– Finished goods manufacturing in China is technically not legal enforcement is ramping up as China wants revenue
– American API manufacturing is nearly impossible due to environmental regulations and cost
– Anyone entering the industry now needs real money, real testing, and real infrastructure — the easy days are over
– Janoshik-style third party testing is now essential fake, empty, and underdosed vials are flooding the market

📺 Subscribe for more no-fluff peptide education every week.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/

Follow Trevor Kruder:
Website: https://alphabiomedlabs.com
Website: https://www.trevorkruder.com
Instagram: https://www.instagram.com/trevorkruder

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.

Welcome back, warriors! In this week's Peptide Q&A, JD Denham and William T. Haas cover TRT and hair loss fears, severe histamine reactions, HCG vs Clomid for fertility on TRT, autoimmune protocols, building muscle with Charcot-Marie-Tooth disease, and cognitive function peptides for older men.

Chapters:
00:00 – Fatherhood, Family & Travel Plans
07:05 – Relationships, Marriage & Commitment
14:29 – New Producer & Community Update
17:18 – TRT, Hair Loss & Optimization
24:18 – Gut Health & Autoimmune Peptides
28:37 – Healing Shoulder Injuries with Peptides
32:35 – Retatrutide Progress & Weight Loss
37:23 – Growth Hormone, Longevity & Brain Health
42:58 – TRT Protocols, Fertility & HCG
50:52 – Preserving Muscle After 50
54:34 – Histamine Reactions & Injection Issues
58:23 – Autoimmune Support & Closing Thoughts

We cover:
• TRT & Hair Loss at 47: Why DHT is the culprit, why a very low starting dose may minimize the risk, and why how you feel should outrank how much hair you have
• Autoimmune, Gut Healing & Inflammation: Why oral BPC and KPV beat Klow for gut-focused protocols, the TA-1 and LL-37 VIP sequence for autoimmune, and what to watch for during flares
• Shoulder Stabilization Recovery at 21: Why aggressive daily dosing of BPC and TB-500 beats conservative approaches and why movement accelerates healing
• Retatrutide Not Moving the Scale: Why feeling leaner and weight staying flat means body recomposition is working and why itchy skin typically resolves on its own
• Blood Work Panels for a 64-Year-Old: Why DEXA scan, IGF-1, ApoB, ferritin, thyroid panel and homocysteine matter most and where to find the full list in the school
• TRT at 33 with Testosterone at 145: Why N-Clomiphene beats Clomid, when to use HCG vs when to save it for fertility, and how to read early estrogen warning signs
• Building Muscle with Charcot-Marie-Tooth & Post-Menopause: Why adding Ipa to Tesamorelin, cycling IGF-1 LR3 short term, and potentially pulling Retatrutide to eat more may be the real answer
• Severe Full-Body Histamine Reaction: Why CJC is the most common culprit, how to systematically reintroduce one compound at a time, and why slower injection into fat reduces reactions
• Chilblains & Cold Feet from Autoimmune: Why KPV injectable, TA-1, Wolverine and oral BPC beat prescription antibiotics for this condition
• Cognitive Function Peptides at 64: Why Dihexa, Pinealon, Cerebrolysin, Semax, Selank and Modafinil are the right tools and how they each work differently on the brain

📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.

You're a warrior. Act like one.

Follow us on social media:
JD's Instagram: https://www.instagram.com/jddenhamofficial/
Will's Instagram: https://www.instagram.com/williamthaas/
Join The Community: https://www.skool.com/peptideresearchinstitute/about
Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/